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| Status |
Public on Feb 21, 2012 |
| Title |
Comparison of Hepatocyte nuclear factor 4 alpha developmental and temporal knockout mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
The goal of this experiment was to distinguish those genes regulated following acute HNF4alpha depletion compared to a developmental knockout model where gene compensation may comfound results. Expression profile of livers from 8 week old male Hnf4alpha Flox mice that express either albumin cre or the tamoxifen inducible ErT2-albumin cre for liver-specific deletion. Mice were fed a control diet or tamoxifen diet in the case of the ErT2-albumin cre to induce recombination.
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| Overall design |
Six-condition experiment, H4N vs H4T vs H4EN vs H4ET vs H4CN vs H4CP. Biological replicates: 4 samples each group.
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| |
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| Contributor(s) |
Bonzo JA, Matsubara T, Gonzalez FJ |
| Citation(s) |
22241473 |
| |
| Submission date |
Dec 20, 2011 |
| Last update date |
Jan 12, 2017 |
| Contact name |
Jessica Bonzo |
| Organization name |
NCI/NIH
|
| Department |
CCR
|
| Lab |
Laboratory of Metabolism
|
| Street address |
9000 Rockville Pike, Building 37, Rm3112
|
| City |
Bethesda |
| State/province |
MD |
| ZIP/Postal code |
20892 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL7202 |
Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version) |
|
| Samples (24)
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| Relations |
| BioProject |
PRJNA151005 |
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