|
| Status |
Public on Mar 08, 2013 |
| Title |
Dual inactivation of Akt and ERK by small molecule TIC10 signals Foxo3a nuclear translocation, TRAIL gene induction and potent anti-tumor effects |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
TIC10-induced transcriptional changes at 48hrs in HCT116 p53-null cells (10uM).
|
| |
|
| Overall design |
Six samples of HCT116 p53-null cells with TIC10 (10uM) or DMSO treatment. Three replicates each.
|
| |
|
| Contributor(s) |
Allen JE, El-Deiry WS |
| Citation(s) |
23390247 |
| |
| Submission date |
Dec 06, 2011 |
| Last update date |
Aug 13, 2018 |
| Contact name |
Joshua E Allen |
| E-mail(s) |
[email protected]
|
| Organization name |
Penn State Hershey Medical Ctr
|
| Lab |
ALLEN
|
| Street address |
500 University Drive
|
| City |
Hershey |
| State/province |
PA |
| ZIP/Postal code |
17033 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA149831 |
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