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Series GSE33455 Query DataSets for GSE33455
Status Public on Jan 01, 2012
Title Expression data from docetaxel-resistant prostate cancer cell lines
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Docetaxel-based chemotherapy is the standard first-line therapy in metastatic castration-resistant prostate cancer. However, most patients eventually develop resistance to this treatment.
The aim of the study was to identify key molecular genes and networks associated with docetaxel resistance in 2 models of docetaxel-resistant castration-resistant prostate cancer cell lines.
 
Overall design DU-145 and PC-3 cells were converted to docetaxel-resistant cells, DU-145R and PC-3R, respectively. Whole-genome arrays were used to compare global gene expression between these 4 cell lines. Arrays were performed by triplicate for each cell line.
 
Contributor(s) Marín-Aguilera M, Kalko SG, Mellado B
Citation(s) 22027694
Submission date Nov 03, 2011
Last update date Mar 12, 2020
Contact name Mercedes Marín-Aguilera
E-mail(s) [email protected]
Organization name Fundació Clínic per a la Recerca Biomèdica
Street address Villarroel 170
City Barcelona
ZIP/Postal code 08036
Country Spain
 
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (12)
GSM827130 DU-145-rep1
GSM827131 DU-145-rep2
GSM827132 DU-145-rep3
Relations
Affiliated with GSE67157
BioProject PRJNA148679

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE33455_RAW.tar 56.5 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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