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Status |
Public on Sep 30, 2011 |
Title |
Subcutaneous adipose tissue: comparison of weight maintainence and weight regain following an 8-week low calorie diet |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
The present study was designed to identify determinants that foreshadow successful weight maintenance. More specifically, we examined whether subcutaneous adipose tissue (scAT) gene expression of participants who experience successful weight maintenance following caloric restriction differed from that of participants who regain weight.
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Overall design |
Forty women followed a dietary protocol consisting of an 8-week low calorie diet (LCD) and a 6-month weight maintenance phase. At the end of the protocol, participants were classified as weight maintainers (WM; 0-10% weight regain) and weight regainers (WR; 50-100% weight regain). Anthropometric measurements, plasma parameters, and scAT biopsies were taken before and after the LCD. Adipose tissue gene expression profiles were studied in all individuals before and after the LCD.
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Contributor(s) |
Mutch DM, Wong M, Clément K |
Citation(s) |
22030226 |
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Submission date |
Sep 29, 2010 |
Last update date |
Feb 22, 2018 |
Contact name |
David M Mutch |
E-mail(s) |
[email protected]
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Phone |
+1-519-824-4120
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Organization name |
University of Guelph
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Department |
Human Health & Nutritional Sciences
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Lab |
ANNU 308
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Street address |
50 Stone Road East
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City |
Guelph |
State/province |
Ontario |
ZIP/Postal code |
N1G 2W1 |
Country |
Canada |
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Platforms (1) |
GPL4133 |
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version) |
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Samples (80)
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Relations |
BioProject |
PRJNA132783 |