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| Status |
Public on Aug 01, 2005 |
| Title |
Mechanical Ventilation Augments LPS-induced Lung Injury |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
This experiment investigated the role of mechanical ventilation (MV) in modulating lung's transcriptional response to LPS. Twenty four C57/B6 male mice were randomized to four groups: 1. Control, 2. MV, 3. LPS and 4. MV+LPS. Expression profiling of whole lungs revealed a significant augmentation of the transcriptional response in the combined MV+LPS group relative to the other 3 conditions.
Keywords: repeat sample
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| Contributor(s) |
Altemeier WA, Matute-Bello G, Gharib SA, Glenny RW, Martin T, Liles W |
| Citation(s) |
16116230 |
| |
| Submission date |
Mar 16, 2005 |
| Last update date |
Oct 19, 2022 |
| Contact name |
Sina Gharib |
| E-mail(s) |
[email protected]
|
| Organization name |
University of Washington
|
| Department |
Medicine
|
| Street address |
850 Republican St.
|
| City |
Seattle |
| State/province |
WA |
| ZIP/Postal code |
98109 |
| Country |
USA |
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| Platforms (1) |
| GPL339 |
[MOE430A] Affymetrix Mouse Expression 430A Array |
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| Samples (24)
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| Relations |
| BioProject |
PRJNA91623 |
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