NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Series GSE227505 Query DataSets for GSE227505
Status Public on Aug 21, 2023
Title scRNA-Seq analysis of unperturbed and perturbed HSC, MPP1 and MPP2 cells of miR-221/222-proficient and deficient mice.
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary We have studied the effect of miR-221/222-deficiency on early hematopoietic stem and progenitor cell quiescence activation in unperturbed and after short-term perturbed hematopoiesis.
 
Overall design Comparative gene expression profiling analysis on unperturbed and perturbed HSC, MPP1 and MPP2 cell populations of miR-221/222-proficient and deficient mice using single-cell RNA-Seq.
 
Contributor(s) Jani PK, Petkau G, Kawano Y, Klemm U, Guerra G, Heinz GA, Heinrich F, Durek P, Mashreghi M, Melchers F
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Mar 16, 2023
Last update date Aug 22, 2023
Contact name Frederik Richard Heinrich
E-mail(s) [email protected]
Organization name Deutsches Rheumaforschungszentrum Berlin
Department Bioinformatics
Lab AG Mashreghi
Street address Chariteplatz 1
City Berlin
State/province Berlin
ZIP/Postal code 10117
Country Germany
 
Platforms (1)
GPL30172 NextSeq 2000 (Mus musculus)
Samples (12)
GSM7101904 HSC_GEX_Unpert
GSM7101905 MPP1_GEX_Unpert
GSM7101906 MPP2_GEX_Unpert
Relations
BioProject PRJNA945410

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE227505_HSC.filtered_feature_bc_matrix.h5 10.2 Mb (ftp)(http) H5
GSE227505_HSC_no3.filtered_feature_bc_matrix.h5 13.1 Mb (ftp)(http) H5
GSE227505_MPP1.filtered_feature_bc_matrix.h5 16.9 Mb (ftp)(http) H5
GSE227505_MPP1_no3.filtered_feature_bc_matrix.h5 17.3 Mb (ftp)(http) H5
GSE227505_MPP2.filtered_feature_bc_matrix.h5 12.1 Mb (ftp)(http) H5
GSE227505_MPP2_no3.filtered_feature_bc_matrix.h5 8.0 Mb (ftp)(http) H5
GSE227505_RAW.tar 10.0 Kb (http)(custom) TAR (of CSV)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap