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| Status |
Public on Feb 11, 2005 |
| Title |
Spinal Cord Trauma Supraspinal Tracts |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
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| Summary |
Summary: Spinal cord injury (SCI) is a damage to the spinal cord induced by trauma or disease resulting in a loss of mobility or feeling. SCI is characterized by a primary mechanical injury followed by a secondary injury in which several molecular events are altered in the spinal cord often resulting in loss of neuronal function. Analysis of the areas directly (spinal cord) and indirectly (raphe and sensorimotor cortex) affected by injury will help understanding mechanisms of SCI.
Hypothesis: Areas of the brain primarily affected by spinal cord injury are the Raphe and the Sensorimotor cortex thus gene expression profiling these two areas might contribute understanding the mechanisms of spinal cord injury.
Specific Aim: The project aims at finding significantly altered genes in the Raphe and Sensorimotor cortex following an induced moderate spinal cord injury in T9.
Keywords: other
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| Contributor(s) |
Faden A |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Feb 11, 2005 |
| Last update date |
Oct 01, 2019 |
| Contact name |
Eric P Hoffman |
| E-mail(s) |
[email protected]
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| Organization name |
Binghamton University - SUNY
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| Department |
Pharmaceutical Sciences
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| Street address |
PO Box 6000
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| City |
Binghamton |
| State/province |
NY |
| ZIP/Postal code |
13902 |
| Country |
USA |
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| Platforms (3) |
| GPL85 |
[RG_U34A] Affymetrix Rat Genome U34 Array |
| GPL86 |
[RG_U34B] Affymetrix Rat Genome U34 Array |
| GPL87 |
[RG_U34C] Affymetrix Rat Genome U34 Array |
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| Samples (244)
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| Relations |
| BioProject |
PRJNA91389 |
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