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Status |
Public on Mar 10, 2023 |
Title |
Expression data from mothers, placentas, and newborns in the Democratic Republic of Congo |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
Maternal stress has long been associated with lower birthweight but mechanisms remain elusive. This study explored how maternal stress may impact changes in gene expression within a cohort of mother-placenta-newborn triads in the eastern Democratic Republic of Congo We used microarrays to detail the global programme of gene expression underlying the impact of maternal stress on newborn birthweight and identified that global placental gene expression may partially mediate the negative impact of maternal war stress on newborn birthweight.
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Overall design |
Samples from Homo sapiens sapiens mother, newborn, and placenta triads were collected at the time of birth for RNA extraction and hybridization on the Human Clariom D microarray (Affymetrix GeneChip system).
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Contributor(s) |
Hsiao CJ, Mulligan CJ |
Citation missing |
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Submission date |
Mar 09, 2023 |
Last update date |
Mar 12, 2023 |
Contact name |
Chu Hsiao |
E-mail(s) |
[email protected]
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Organization name |
University of Florida
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Department |
Anthropology
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Lab |
Mulligan Lab
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Street address |
2033 Mowry Rd
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City |
Gainesville |
State/province |
FL |
ZIP/Postal code |
32610 |
Country |
USA |
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Platforms (1) |
GPL23126 |
[Clariom_D_Human] Affymetrix Human Clariom D Assay [transcript (gene) version] |
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Samples (279)
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Relations |
BioProject |
PRJNA942634 |