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| Status |
Public on Aug 25, 2023 |
| Title |
Genetic and dietary modulators of inflammation in the gastro-intestinal tract of BXD genetic reference population |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Transcriptome data measured by microarray in colon of the BXD mouse genetic diversity model under a standard chow or a high fat diet at a fastd state.
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| Overall design |
At 29 weeks of age, mice of 52 BXD strains including parental C57BL/6J and DBA/2J strains were fasted overday and then were sacrificed. Phenotyping were performed and multi-organ were flash-frozen and bio-banked for future use, the assoiacted datasets are mentioned in the paper. In this study, proximal colon samples were collected and immediately frozen in liquid nitrogen for RNA extraction and RNEasy cleanup. Each dietary and strain cohort consisted of ~5 animals which were prepared independently then pooled evenly by µg RNA before the Affymetrix arrays were run.
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| Web link |
https://elifesciences.org/reviewed-preprints/87569
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| Contributor(s) |
Auwerx J, Li X, Bachmann A, Rapin A, Sleiman MB, Morel J |
| Citation(s) |
37855835 |
| |
| Submission date |
Feb 22, 2023 |
| Last update date |
Oct 26, 2023 |
| Contact name |
Xiaoxu Li |
| E-mail(s) |
[email protected]
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| Organization name |
EPFL
|
| Street address |
Station 15 - CH
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| City |
Lausanne |
| ZIP/Postal code |
1015 |
| Country |
Switzerland |
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| Platforms (1) |
| GPL23038 |
[Clariom_S_Mouse] Affymetrix Clariom S Assay, Mouse (Includes Pico Assay) |
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| Samples (99)
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| Relations |
| BioProject |
PRJNA937625 |
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