|
Status |
Public on Feb 17, 2023 |
Title |
Human Hematopoietic Stem Cell Vulnerability to Ferroptosis [scRNA-seq] |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by high throughput sequencing
|
Summary |
To investigate differential gene expression of CD34+CD45RA-CD90+ cells with MYSM1 deficiency achieved by CRISPR editing
|
|
|
Overall design |
Single cell transcriptomic profiling of CD34+CD45RA-CD90+ cells edited by AAVS1 and MYSM1 guide RNAs
|
Web link |
https://doi.org/10.1016/j.cell.2023.01.020
|
|
|
Contributor(s) |
Zhao J, Sankaran V |
Citation(s) |
36803603 |
|
Submission date |
Dec 16, 2022 |
Last update date |
May 19, 2023 |
Contact name |
Jiawei Zhao |
E-mail(s) |
[email protected]
|
Organization name |
Boston Children's Hospital
|
Street address |
1 Blackfan Circle
|
City |
Boston |
State/province |
Massachusetts |
ZIP/Postal code |
02115 |
Country |
USA |
|
|
Platforms (1) |
GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
Samples (2) |
GSM6847346 |
CD34+CD45RA-CD90+ scRNAseq, edited by AAVS1, day 3 post-nucleofection |
GSM6847347 |
CD34+CD45RA-CD90+ scRNAseq, edited by MYSM1, day 4 post-nucleofection |
|
This SubSeries is part of SuperSeries: |
GSE221170 |
Human Hematopoietic Stem Cell Vulnerability to Ferroptosis |
|
Relations |
BioProject |
PRJNA915208 |