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| Status |
Public on May 10, 2023 |
| Title |
Electroconductive and mechano-competent PUCL@CNT nanohybrid scaffolds guiding neuronal specification of neural stem/progenitor cells |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Neural stem/progenitor cells (NSPCs) exhibited a selective neuron and oligodendrocyte differentiation on the novel conductive, flexible biopolymer composite (PUCL@CNT).
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| Overall design |
To investigate the potential mechanisms in the regulation of directional differentiation, gene expression profiling analysis uses data obtained from RNA Quant-seq of NSPCs at two points.
Comparative gene expression profiling analysis of RNA Quant-seq data for rat NSPCs cultured on the bare PUCL and PUCL@CNT1 platforms under before and after differentiation conditions.
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| Web link |
https://doi.org/10.1016/j.cej.2023.143125
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| Contributor(s) |
Li Y, Lee J, Kim H |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Nov 01, 2022 |
| Last update date |
May 12, 2023 |
| Contact name |
Yu Meng Li |
| E-mail(s) |
[email protected]
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| Organization name |
Institute of Tissue Regeneration Engineering (ITREN)
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| Department |
Department of Nanobiomedical Science
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| Lab |
ITREN
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| Street address |
Pharmacy Bldg, Cheonan 31116, Republic of Korea
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| City |
Cheonan |
| ZIP/Postal code |
31116 |
| Country |
South Korea |
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| Platforms (1) |
| GPL20084 |
Illumina NextSeq 500 (Rattus norvegicus) |
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| Samples (4)
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| GSM6704233 |
1.5d_0: rat NSPCs, PUCL platform, Day1.5,differentiation medium |
| GSM6704234 |
1.5d_1: rat NSPCs, PUCL@CNT1 platform, Day1.5, differentiation medium |
| GSM6704235 |
24h_0: rat NSPCs, PUCL platform, 24h, stemness maintaining medium |
| GSM6704236 |
24h_1: rat NSPCs, PUCL@CNT1 platform, 24h, stemness maintaining medium |
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| Relations |
| BioProject |
PRJNA896621 |
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