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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Oct 12, 2022 |
| Title |
Self-organizing in vitro mouse neural tube organoids mimic embryonic development |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Self-elongating neural tube organoids recapitulate key aspects of the morphology, anterior-posterior patterning, neural crest emergence and neural differentiation of mouse embryo in vivo by self-organization. We used single-cell RNA sequencing (scRNA-seq) to analyse the cell types and to reveal the sequence of transcriptional events in the emergence of neural crest cells and neural differentiation.
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| Overall design |
10x single-cell RNA-seq of mouse neural tube organoids at day 6 (in duplicates), 7, 8, and 10.
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| Contributor(s) |
Park J, Hsiung H, Lutolf M |
| Citation(s) |
36268933 |
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| Submission date |
Oct 07, 2022 |
| Last update date |
Jan 11, 2023 |
| Contact name |
Matthias Lütolf |
| E-mail(s) |
[email protected]
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| Organization name |
EPFL
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| Department |
Sciences de la vie
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| Lab |
Laboratory of Stem Cell Bioengineering
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| Street address |
AI 1208 Station 15
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| City |
Lausanne |
| ZIP/Postal code |
1015 |
| Country |
Switzerland |
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| Platforms (2) |
| GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA888056 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE214996_D6D10_barcodes.tsv.gz |
57.1 Kb |
(ftp)(http) |
TSV |
| GSE214996_D6D10_features.tsv.gz |
80.6 Kb |
(ftp)(http) |
TSV |
| GSE214996_D6D10_matrix.mtx.gz |
208.3 Mb |
(ftp)(http) |
MTX |
| GSE214996_D6D10_metadata.tsv.gz |
3.5 Mb |
(ftp)(http) |
TSV |
| GSE214996_D6_barcodes.tsv.gz |
21.0 Kb |
(ftp)(http) |
TSV |
| GSE214996_D6_features.tsv.gz |
68.8 Kb |
(ftp)(http) |
TSV |
| GSE214996_D6_matrix.mtx.gz |
69.1 Mb |
(ftp)(http) |
MTX |
| GSE214996_D6_metadata.tsv.gz |
1.3 Mb |
(ftp)(http) |
TSV |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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