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Series GSE212492 Query DataSets for GSE212492
Status Public on Sep 04, 2022
Title Effect of aging and dFOXO knockout on small RNA in Ago1 and Ago2 RNA-induced silencing complexes
Organism Drosophila melanogaster
Experiment type Other
Summary To examine the effect of loss of dFOXO on Ago1 and Ago2 RISC loading in aging animals, we sequenced RNA immunoprecipitated from Ago1 and Ago2 RISC collected from whole wildtype (wDah) and dFOXO-null (dfoxoΔ94) flies at young (5 days) and old (35 days) age. dFOXO is a transcription factor that regulates Ago1 and Ago2 as well as lifespan.
 
Overall design Two biological replicates of RNA immunoprecipitated from Ago1 and Ago2 from whole control (wDah) and dFOXO-null flies at were collected at young and old ages
 
Contributor(s) Gartland S, Marr MT
Citation(s) 36383505
Submission date Sep 01, 2022
Last update date Dec 01, 2022
Contact name Siobhan Gartland
Organization name Brandeis University
Department Biology
Lab Marr
Street address 415 SOUTH STREET
City Waltham
State/province MA
ZIP/Postal code 02453
Country USA
 
Platforms (1)
GPL19132 Illumina NextSeq 500 (Drosophila melanogaster)
Samples (32)
GSM6533686 wDah_female_Ago1IP_05d_exp1
GSM6533687 wDah_female_Ago2IP_05d_exp1
GSM6533688 wDah_male_Ago1IP_05d_exp1
This SubSeries is part of SuperSeries:
GSE212494 The small RNA landscape across age and loss of dFOXO in Drosophila
Relations
BioProject PRJNA875631

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE212492_AgoIP_mappedtodm6_normalized.txt.gz 170.1 Kb (ftp)(http) TXT
GSE212492_AgoIP_mappedtodm6_prenormalization.txt.gz 65.8 Kb (ftp)(http) TXT
GSE212492_AgoIP_mappedtomiRNAstransposons_21nt_normalized.txt.gz 32.8 Kb (ftp)(http) TXT
GSE212492_AgoIP_mappedtomiRNAstransposons_21nt_prenormalization.txt.gz 11.8 Kb (ftp)(http) TXT
GSE212492_AgoIP_mappedtomiRNAstransposons_normalized.txt.gz 43.4 Kb (ftp)(http) TXT
GSE212492_AgoIP_mappedtomiRNAstransposons_prenormalization.txt.gz 16.5 Kb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record
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