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| Status |
Public on Aug 09, 2023 |
| Title |
Cocaine addiction-like behaviors are associated with long-term changes in gene regulation, energy metabolism, and GABAergic inhibition within the amygdala |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
This SuperSeries is composed of the SubSeries listed below.
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| Overall design |
Refer to individual Series
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| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| F31 DA056226 |
Computational analysis of single-nucleus sequencing data for studying the cell type-specific basis of opioid use disorders |
THE SALK INSTITUTE FOR BIOLOGICAL STUDIES |
Jessica Lu Zhou |
| U01 DA050239 |
Single-cell resolution analysis of chromatin accessibility and gene expression changes in a model of drug addiction |
THE REGENTS OF THE UNIV. OF CALIF., UNIV. OF CALIF., SAN DIEGO |
Francesca Telese |
| P50 DA037844 |
Center for Genetic Studies of Drug Abuse in Outbred Rats |
THE REGENTS OF THE UNIV. OF CALIF., UNIV. OF CALIF., SAN DIEGO |
ABRAHAM A PALMER |
| U01 DA043799 |
Identification of Genetic Variants that Contribute to Compulsive Cocaine Intake inRats |
THE REGENTS OF THE UNIV. OF CALIF., UNIV. OF CALIF., SAN DIEGO |
Olivier George |
| U01 DA043799 |
Identification of Genetic Variants that Contribute to Compulsive Cocaine Intake inRats |
THE REGENTS OF THE UNIV. OF CALIF., UNIV. OF CALIF., SAN DIEGO |
ABRAHAM A PALMER |
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| Submission date |
Aug 31, 2022 |
| Last update date |
Aug 10, 2023 |
| Contact name |
Jessica Lu Zhou |
| Organization name |
University of California San Diego
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| Street address |
9500 Gilman Drive
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| City |
La Jolla |
| State/province |
California |
| ZIP/Postal code |
92093-0603 |
| Country |
USA |
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| Platforms (2) |
| GPL20084 |
Illumina NextSeq 500 (Rattus norvegicus) |
| GPL25947 |
Illumina NovaSeq 6000 (Rattus norvegicus) |
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| Samples (35)
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| GSM6529590 |
RFID 933000320046084 (naïve), snRNA-seq |
| GSM6529591 |
RFID 933000320046077 (naïve), snRNA-seq |
| GSM6529592 |
RFID 933000120138609 (low), snRNA-seq |
| GSM6529593 |
RFID 933000320186802 (high), snRNA-seq |
| GSM6529594 |
RFID 933000320047225 (high), snRNA-seq |
| GSM6529595 |
RFID 933000320046609 (high), snRNA-seq |
| GSM6529596 |
RFID 933000320047001 (low), snRNA-seq |
| GSM6529597 |
RFID 933000320047132 (low), snRNA-seq |
| GSM6529598 |
RFID 933000320186801 (naïve), snRNA-seq |
| GSM6529599 |
RFID 933000320046621 (naïve), snRNA-seq |
| GSM6529600 |
RFID 933000320046625 (naïve), snRNA-seq |
| GSM6529601 |
RFID 933000320047104 (low), snRNA-seq |
| GSM6529602 |
RFID 933000320045674 (high), snRNA-seq |
| GSM6529603 |
RFID 933000120138730 (high), snRNA-seq |
| GSM6529604 |
RFID 933000120138414 (low), snRNA-seq |
| GSM6529605 |
RFID 933000320046549 (naïve), snRNA-seq |
| GSM6529606 |
RFID 933000320186811 (high), snATAC-seq |
| GSM6529607 |
RFID 933000320047166 (low), snATAC-seq |
| GSM6529608 |
RFID 933000320187130 (naïve), snATAC-seq |
| GSM6529609 |
RFID 933000320047651 (naïve), snATAC-seq |
| GSM6529610 |
RFID 933000320047161 (naïve), snATAC-seq |
| GSM6529611 |
RFID 933000120138730 (high), snATAC-seq |
| GSM6529612 |
RFID 933000120138414 (low), snATAC-seq |
| GSM6529613 |
RFID 933000320187092 (high), snATAC-seq |
| GSM6529614 |
RFID 933000320047019 (high), snATAC-seq |
| GSM6529615 |
RFID 933000320046611 (low), snATAC-seq |
| GSM6529616 |
RFID 933000320045785 (low), snATAC-seq |
| GSM6529617 |
RFID 933000320047174 (naïve), snATAC-seq |
| GSM7498809 |
Central amygdala, snRNA-seq |
| GSM7498810 |
Basolateral amygdala, snRNA-seq |
| GSM7498844 |
Central amygdala, snATAC-seq |
| GSM7498845 |
Basolateral amygdala, snATAC-seq |
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| This SuperSeries is composed of the following SubSeries:
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| GSE212415 |
A single-cell atlas of gene expression and chromatin accessibility changes associated with cocaine addiction in the rat amygdala [snRNA-seq] |
| GSE212416 |
A single-cell atlas of gene expression and chromatin accessibility changes associated with cocaine addiction in the rat amygdala [snATAC-seq] |
| GSE235314 |
A single-cell atlas of gene expression and chromatin accessibility changes associated with cocaine addiction in the rat amygdala (snRNA-Seq Multiome) |
| GSE235317 |
A single-cell atlas of gene expression and chromatin accessibility changes associated with cocaine addiction in the rat amygdala (snATAC-Seq Multiome) |
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| Relations |
| BioProject |
PRJNA875396 |
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