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| Status |
Public on Aug 29, 2022 |
| Title |
CEACAM 1, 3, 5 and 6 -positive classical monocytes correlate with interstitial lung disease in early systemic sclerosis |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
To clarify the characteristics of CEACAM-positive monocytes in systemic sclerosis (SSc), we performed gene expression microarrays between CEACAM-positive and CEACAM-negative classical monocytes from diffused cutaneous systemic sclerosis(dcSSc) patients. We further analyzed expression levels of each subtype of CEACAM on monocytes from dcSSc by flow cytometry and performed gene expression microarrays between CEACAM1+CEACAM6- and CEACAM1-CEACAM6+ monocytes.
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| Overall design |
Gene expression analysis was performed between CEACAM+ and CEACAM- monocytes from one dcSSc patient. Gene expression analysis was performed between CEACAM1+CEACAM6- and CEACAM1-CEACAM6+ monocytes from another dcSSc patient.
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| Contributor(s) |
Yokoyama K, Mitoma H, Kawano S, Yamauchi Y, Wang Q, Ayano M, Kimoto Y, Nobuyuki O, Arinobu Y, Akashi K, Horiuchi T, Niiro H |
| Citation(s) |
36341379 |
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| Submission date |
Jul 04, 2022 |
| Last update date |
Nov 13, 2022 |
| Contact name |
Kana Yokoyama |
| Organization name |
Kyushu University Hospital
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| Department |
Department of Medicine and Biosystemic Sciences
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| Street address |
3-1-1, Maidashi, Higashi-Ku
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| City |
Fukuoka |
| State/province |
Fukuoka |
| ZIP/Postal code |
812-8582 |
| Country |
Japan |
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| Platforms (1) |
| GPL23126 |
[Clariom_D_Human] Affymetrix Human Clariom D Assay [transcript (gene) version] |
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| Samples (2) |
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| This SubSeries is part of SuperSeries: |
| GSE207425 |
CEACAM 1, 3, 5 and 6 -positive classical monocytes correlate with interstitial lung disease in early systemic sclerosis |
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| Relations |
| BioProject |
PRJNA855449 |
