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| Status |
Public on Jan 03, 2023 |
| Title |
Transit-amplifying lineage states convey the susceptibility of PTEN and P53 loss to gliomagenesis [PPO2_Bulk_RNA-seq] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To investigate the glioma mouse model by knocking out Pten and Trp53 in embryonal Olig2 positive cells in glioma pathogenesis.
We then performed gene expression profiling analysis using data obtained from RNA-seq of 4 PPO2 tumor tissue with 2 Control cortex tissue.
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| |
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for PPO2 glioma and wild type control cortex.
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| |
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| Contributor(s) |
Lu QR, Verma RK, Xin D |
| Citation(s) |
36634201 |
| |
| Submission date |
Apr 15, 2022 |
| Last update date |
Jun 29, 2023 |
| Contact name |
Richard Q. Lu |
| E-mail(s) |
[email protected], [email protected]
|
| Phone |
15133941514
|
| Organization name |
Cincinnati Childrens Hosp Med Ctrl
|
| Department |
CBDI
|
| Lab |
Lu Lab, T6 525
|
| Street address |
3333 Burnet Avenue
|
| City |
CINCINNATI |
| State/province |
OH |
| ZIP/Postal code |
45229 |
| Country |
USA |
| |
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| Platforms (1) |
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| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE200892 |
Olig1/2-expressing intermediate lineage progenitors are predisposed to PTEN/p53-loss-induced gliomagenesis and harbor specific therapeutic vulnerabilities |
|
| Relations |
| BioProject |
PRJNA827150 |
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