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| Status |
Public on Jun 30, 2022 |
| Title |
Next Generation Sequencing Facilitates Quantitative Analysis Transcriptomes of dHL-60 cells after capsaicin processed |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To uncoverthe capsaicin effects on the neutrophil activation, we performed transcriptomic of dHL-60 cells after capsaicin stimulation in degree of different time. this study revealed the functional changes of neutrophils in the presence of capsaicin. The transcriptomic data with different time stimulation gradients can contribute to the revealing of dynamic alternation in gene expression and annotate the time-dependent effect of the neutrophil respond to capsaicin.
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| Overall design |
dHL-60 cells were processed by 400uM capsaicin for 8 hours, 16 hours, and 24 hours.
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| Web link |
https://pubmed.ncbi.nlm.nih.gov/36071055/
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| |
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| Contributor(s) |
Chen K, Chen Y |
| Citation(s) |
36071055 |
| |
| Submission date |
Mar 10, 2022 |
| Last update date |
Jun 08, 2023 |
| Contact name |
Kexin Chen |
| E-mail(s) |
[email protected]
|
| Phone |
86-13896212948
|
| Organization name |
West China hospital
|
| Department |
Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu, China
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| Lab |
Lab of Inflammatory bowel disease, Frontiers Science Center for Disease-Related Molecular Network
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| Street address |
No.37 guoxue Lane, Wuhou District, Chengdu city
|
| City |
Chengdu |
| State/province |
Sichuan |
| ZIP/Postal code |
610044 |
| Country |
China |
| |
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| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (12)
|
| GSM5944741 |
Differentiated HL-60 neutrophil-like cells rep-1 |
| GSM5944742 |
Differentiated HL-60 neutrophil-like cells rep-2 |
| GSM5944743 |
Differentiated HL-60 neutrophil-like cells rep-3 |
| GSM5944744 |
Differentiated HL-60 neutrophil-like cells processed by capsaicin for 8 hours rep-1 |
| GSM5944745 |
Differentiated HL-60 neutrophil-like cells processed by capsaicin for 8 hours rep-2 |
| GSM5944746 |
Differentiated HL-60 neutrophil-like cells processed by capsaicin for 8 hours rep-3 |
| GSM5944747 |
Differentiated HL-60 neutrophil-like cells processed by capsaicin for 16 hours rep-1 |
| GSM5944748 |
Differentiated HL-60 neutrophil-like cells processed by capsaicin for 16 hours rep-2 |
| GSM5944749 |
Differentiated HL-60 neutrophil-like cells processed by capsaicin for 16 hours rep-3 |
| GSM5944750 |
Differentiated HL-60 neutrophil-like cells processed by capsaicin for 24 hours rep-1 |
| GSM5944751 |
Differentiated HL-60 neutrophil-like cells processed by capsaicin for 24 hours rep-2 |
| GSM5944752 |
Differentiated HL-60 neutrophil-like cells processed by capsaicin for 24 hours rep-3 |
|
| Relations |
| BioProject |
PRJNA814524 |
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