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| Status |
Public on Mar 03, 2022 |
| Title |
Abdominal Aortic Aneurysm in C57BL/6J Mice - Male and Female PPE vs. Sham Day 7 |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Transcriptional profiling of infrarenal aorta from male and female mice (10-weeks old, C57BL/6J), treated with either porcine pancreatic elastase (PPE) local infusion or sham operation (saline infusion). Samples harvested 7 days after treatment.
Goal was to examine gene expression in AAA in this model in both genders. Surgical protocol is as described in PMCID: PMC3148686/PMID: 19629030.
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| Overall design |
Two condition experiment, each in male and female, one infrarenal aorta per array. Sham vs. PPE at 1 time point (Day 7). Total arrays 19: female sham 7d (3), female PPE 7d (4), male sham 7d (5), male PPE 7d (7).
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| Contributor(s) |
Spin JM |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Mar 02, 2022 |
| Last update date |
Mar 05, 2022 |
| Contact name |
Joshua M. Spin |
| E-mail(s) |
[email protected]
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| Phone |
650-498-6353
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| Organization name |
Stanford University
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| Department |
Internal Medicine/Cardiovascular Division
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| Lab |
Philip S. Tsao Lab
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| Street address |
300 Pasteur Drive
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| City |
Stanford |
| State/province |
CA |
| ZIP/Postal code |
94305 |
| Country |
USA |
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| Platforms (1) |
| GPL20258 |
[MTA-1_0] Affymetrix Mouse Transcriptome Array 1.0 [transcript (gene) CDF version] |
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| Samples (19)
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| GSM5929409 |
Female, aorta, PPE 7d #1 |
| GSM5929410 |
Female, aorta, PPE 7d #2 |
| GSM5929411 |
Female, aorta, PPE 7d #3 |
| GSM5929412 |
Female, aorta, PPE 7d #4 |
| GSM5929413 |
Male, aorta, sham 7d #1 |
| GSM5929414 |
Male, aorta, sham 7d #2 |
| GSM5929415 |
Male, aorta, sham 7d #3 |
| GSM5929416 |
Male, aorta, sham 7d #4 |
| GSM5929417 |
Male, aorta, sham 7d #5 |
| GSM5929418 |
Male, aorta, PPE 7d #1 |
| GSM5929419 |
Male, aorta, PPE 7d #2 |
| GSM5929420 |
Male, aorta, PPE 7d #3 |
| GSM5929421 |
Male, aorta, PPE 7d #4 |
| GSM5929422 |
Male, aorta, PPE 7d #5 |
| GSM5929423 |
Male, aorta, PPE 7d #6 |
| GSM5929424 |
Male, aorta, PPE 7d #7 |
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| Relations |
| BioProject |
PRJNA811962 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE197748_RAW.tar |
456.6 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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