|
| Status |
Public on Dec 18, 2021 |
| Title |
Transcriptomics and network analysis highlight potential pathways in the pathogenesis of pterygium |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Differential expression comparing active pterygium with atrophic pterygium using data generated from the Brazilian cohort identified differentially expressed genes between the two forms of presentation of this condition
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| |
|
| Overall design |
Samples from nine patients were collected during surgery after photo documentation and clinical characterization of pterygia. Gene expression experiments were performed using Human Clariom D Assay gene chip. Differential gene expression analysis between active and atrophic pterygia was performed using limma package after adjusting variables by age.
|
| Web link |
https://www.nature.com/articles/s41598-021-04248-x
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| |
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| Contributor(s) |
de Guimarães JA, Hounpke BW, Duarte B, Boso AL, Viturino MG, de Carvalho Baptista L, de Melo MB, Alves M |
| Citation(s) |
34997134 |
| |
| Submission date |
Dec 17, 2021 |
| Last update date |
Jan 10, 2022 |
| Contact name |
Juliana Albano de Guimarães |
| Organization name |
School of Medical Sciences of University of Campinas
|
| Department |
Ophthalmology
|
| Street address |
Tessália Vieira de Camargo, 126, Cidade Universitária
|
| City |
Campinas |
| State/province |
SP |
| ZIP/Postal code |
13083-887 |
| Country |
Brazil |
| |
|
| Platforms (1) |
| GPL23126 |
[Clariom_D_Human] Affymetrix Human Clariom D Assay [transcript (gene) version] |
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| Samples (9)
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|
| Relations |
| BioProject |
PRJNA789792 |
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