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| Status |
Public on Sep 15, 2021 |
| Title |
CD49f defines a subset of dysfunctional regulatory T cells circulating in the human peripheral blood |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Integrin CD49f has been reported to modulate various aspects of T cell biology including cell differentiation, migration and functionality. Here we define CD49f as a marker for a subset of dysfunctional human effector Tregs expressing a Th17-like profile in the blood of patients with active inflammatory bowl disease.
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| |
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| Overall design |
RNA profiles of CD49f high and low Tregs extracted from healthy donor peripheral blood mononuclear cells (PBMC).
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| |
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| Contributor(s) |
Lepletier A, Hill M, Straube J |
| Citation(s) |
34504692 |
| |
| Submission date |
Nov 09, 2020 |
| Last update date |
Sep 16, 2021 |
| Contact name |
Jasmin Straube |
| Organization name |
QIMR Berghofer
|
| Street address |
300 Herston Rd
|
| City |
Brisbane |
| State/province |
QLD |
| ZIP/Postal code |
4006 |
| Country |
Australia |
| |
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| Platforms (1) |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA675496 |
| SRA |
SRP291699 |
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