|
| Status |
Public on Nov 01, 2020 |
| Title |
Transcriptional analysis of LAG3 deficient Tregs in an inflamed CNS |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Transcriptonal analysis of Tregs reveal role of LAG3 in stability and function of Tregs in an inflamed CNS
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| |
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| Overall design |
CD45+ cells or CD4 cells were sorted from CNS cells isolated at peaks of diseases in age and sex matched mice(Lag3KO and WT) in which EAE was induced were subject to Gene Expression analysis using the 10x Genomics Single Cell analysis platform.
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| |
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| Contributor(s) |
Thaker YR, Sharpe AH |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Oct 09, 2020 |
| Last update date |
Nov 02, 2020 |
| Contact name |
E JOHN WHERRY |
| Organization name |
University of Pennsylvania
|
| Department |
Systems Pharmacology and Translational Therapeutics,Institute for Immunology
|
| Street address |
421 Curie Blvd,354 BRB II/III
|
| City |
Philadelphia |
| State/province |
PA |
| ZIP/Postal code |
19104 |
| Country |
USA |
| |
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| Platforms (1) |
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| Samples (7)
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| Relations |
| BioProject |
PRJNA668390 |
| SRA |
SRP286928 |
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