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| Status |
Public on Sep 05, 2020 |
| Title |
Lymphatic endothelial cells contribute to blood vessel formation in tumours |
| Organisms |
Mus musculus; blank sample |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Using multicolor lineage tracing, in vivo time-lapse imaging and single cell transcriptional profiling in a mouse glioma model, we identify tumour blood endothelial cells carrying a Csf1r lineage trace. These Csf1r lineage endothelial cells (CLECs) form up to 10% of the tumour vasculature and express endothelial cell markers as well as a unique set of genes that can also be found in single cell transcriptome data of tumour endothelium from various human tumours.
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| |
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| Overall design |
The transcriptomes of 768 single cells were sequenced (scRNAseq) after FACS sorting.
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| |
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| Contributor(s) |
Rambow F |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Sep 04, 2020 |
| Last update date |
Jun 04, 2021 |
| Contact name |
Florian Rambow |
| E-mail(s) |
[email protected]
|
| Organization name |
VIB
|
| Street address |
Herestraat 49 box 912
|
| City |
Leuven |
| ZIP/Postal code |
3000 |
| Country |
Belgium |
| |
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| Platforms (2) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
| GPL29107 |
Illumina NextSeq 500 (blank sample) |
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| Samples (768)
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| Relations |
| BioProject |
PRJNA661541 |
| SRA |
SRP280130 |
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