|
| Status |
Public on Aug 12, 2021 |
| Title |
Super-enhancer based development of an endothelial specific lentiviral vector |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Hypoxia-regulated endothelial-specific lentiviral vector that can be used for endothelial-targeted gene therapy.
|
| |
|
| Overall design |
Construction of Lentiviral vectors containing endothelial-specific enhancer driving expression of reporter gene, vectors evaluation in vitro and Knock out validation studies with CRISPR/Cas9, followed by RNA-Seq in EA.hy926.
|
| |
|
| Contributor(s) |
Laram-Karam N, Mushimiyimana I, Kaikkonen-Määttä M, Niskanen H, Ylä-Herttuala S |
| Citation(s) |
34320216 |
| |
| Submission date |
Jun 04, 2020 |
| Last update date |
Aug 14, 2021 |
| Contact name |
Minna Kaikkonen-Määttä |
| Organization name |
A. I. Virtanen Institute
|
| Street address |
P. O. Box 1627
|
| City |
Kuopio |
| ZIP/Postal code |
70721 |
| Country |
Finland |
| |
|
| Platforms (1) |
|
| Samples (8)
|
|
| Relations |
| BioProject |
PRJNA637380 |
| SRA |
SRP266195 |
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