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| Status |
Public on Feb 23, 2021 |
| Title |
NG-Capture C analysis of 35 gene loci regulated by Fra-1 in MDA-MB-231 cells |
| Organism |
Homo sapiens |
| Experiment type |
Other
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| Summary |
In the article "Fra-1 regulates its target genes via binding to remote enhancers without exerting major control on chromatin architecture in triple negative breast cancers" by Bejjani et al., we used NG Capture-C approach to identify regulatory elements interacting with the promoters of 35 Fra-1 regulated genes in the triple negative breast cancer cell line MDA-MB-231
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| Overall design |
Identification of chromatin interactions by NG Capture-C between distal regulatory elements and the promoters of 35 Fra-1 regulated genes in MDA-MB-231 cells in presence and absence of Fra-1 (siRNA approach)
The 35 assayed genes include:
ABTB2
ASB1
CD44
CDCP1
EDN1
EMP1
FNDC3B
FOSL1
GALNT2
HEG1
HES1
HK2
HMGA1
ID1
IL8
KRT80
LIPH
LRP10
MAP2K1
MXD1
MYO10
PDE2A
PITPNC1
RPSAP52
SMAD6
SOX9
SRGAP1
SSFA2
TCF7L2
TES
TGFB2
TMC6
TNS3
TSPAN2
ZNF114
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| Web link |
https://doi.org/10.1093/nar/gkab053
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| Contributor(s) |
Bejjani F, Tolza C, Downes D, Hughes J, Piechaczyk M, Jariel-Encontre I |
| Citation(s) |
33533919, 37464380 |
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| Submission date |
Mar 11, 2020 |
| Last update date |
Sep 12, 2023 |
| Contact name |
Isabelle Jariel-Encontre |
| E-mail(s) |
[email protected]
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| Phone |
00 33 (0)4 11 28 31 53
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| Organization name |
IRCM-U1194- INSERM
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| Street address |
208 Avenue des Apothicaires
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| City |
Montpellier |
| State/province |
Montpellier Cedex5 |
| ZIP/Postal code |
34298 |
| Country |
France |
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| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
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| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE146825 |
Transcriptional regulation by Fra-1 in triple negative breast cancers |
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| Relations |
| BioProject |
PRJNA612052 |
| SRA |
SRP252455 |
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