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| Status |
Public on Sep 25, 2019 |
| Title |
VEGF-A drives TOX-dependent T cell exhaustion in anti–PD-1–resistant microsatellite stable colorectal cancers |
| Organisms |
Homo sapiens; Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
VEGF-A drives TOX-dependent T cell exhaustion in anti–PD-1–resistant microsatellite stable colorectal cancers
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| Overall design |
Normal colon, MC38-OVA, Control siRNA transfected, TOX siRNA transfected CD8 T cell, Control CD8 T cell, VEGF-A treated CD8 T cell
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| Contributor(s) |
Kim C, Jang M, Kim Y, Leem G, Kim K, Lee H, Kim T, Choi S, Kim H, Han J, Kwon M, Kim J, Lee A, Nam S, Bae S, Lee S, Shin S, Ahn J, Lee K, Park S, Jung I, Park S, Kim H, Min B, Shin E |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Aug 13, 2019 |
| Last update date |
Dec 06, 2019 |
| Contact name |
Chang Gon Kim |
| E-mail(s) |
[email protected]
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| Organization name |
Korea Advanced Institute of Science and Technology
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| Street address |
291 Daehak-ro
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| City |
Daejeon |
| ZIP/Postal code |
03772 |
| Country |
South Korea |
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| Platforms (4)
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| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
| GPL21626 |
NextSeq 550 (Mus musculus) |
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| Samples (10)
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| Relations |
| BioProject |
PRJNA560084 |
| SRA |
SRP218261 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE135798_Control_siRNA_specific_peaks.txt.gz |
58.7 Kb |
(ftp)(http) |
TXT |
| GSE135798_MC38-OVA_1.txt.gz |
119.2 Kb |
(ftp)(http) |
TXT |
| GSE135798_MC38-OVA_2.txt.gz |
118.8 Kb |
(ftp)(http) |
TXT |
| GSE135798_MC38-OVA_3.txt.gz |
119.6 Kb |
(ftp)(http) |
TXT |
| GSE135798_Normal_colon_1.txt.gz |
120.7 Kb |
(ftp)(http) |
TXT |
| GSE135798_Normal_colon_2.txt.gz |
120.7 Kb |
(ftp)(http) |
TXT |
| GSE135798_Normal_colon_3.txt.gz |
120.0 Kb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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