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| Status |
Public on Dec 14, 2018 |
| Title |
Comparison of target genes from the pregnane X receptor (Pxr) in the liver vs the intestine [liver] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
We performed a transcriptomic comparison of the Pxr-regulated genes in the liver and intestine (ileum and colon) using microarrays in adult wild-type (WT) vs Pxr-/- C57Bl6/J male mice treated with the rodent specific Pxr ligand pregnenolone 16α-carbonitrile (PCN) (100 mg/kg i.p. once daily for 4 days).
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| Overall design |
PCN-induced changes in gene expression was measured 6h after the last PCN treatment. 4 to 6 animals per group were used.
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| Contributor(s) |
Ellero-Simatos S, Naylies C, Lippi Y |
| Citation(s) |
31374856, 33879258 |
| |
| Submission date |
Dec 13, 2018 |
| Last update date |
Apr 28, 2021 |
| Contact name |
Sandrine Ellero-Simatos |
| E-mail(s) |
[email protected]
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| Organization name |
INRAe
|
| Lab |
TOXALIM
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| Street address |
180 chemin de Tournefeuille
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| City |
Toulouse |
| ZIP/Postal code |
31300 |
| Country |
France |
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| Platforms (1) |
| GPL21163 |
Agilent-074809 SurePrint G3 Mouse GE v2 8x60K Microarray [Probe Name version] |
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| Samples (23)
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| This SubSeries is part of SuperSeries: |
| GSE123804 |
Comparison of target genes from the pregnane X receptor (Pxr) in the liver vs the intestine |
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| Relations |
| BioProject |
PRJNA509892 |
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