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| Status |
Public on Oct 01, 2019 |
| Title |
Role of iron in the regulation of the epithelial-to-mesenchymal transition (ChIP-seq) |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
The biological process termed Epithelial-to-Mesenchymal Transition (EMT) plays a central role in cancer cell invasion, metastasis, self-renewal and resistance to therapy. Here, we characterize using chromatin immunoprecipitation and Next Generation Sequencing the genome-wide H3K9me2 distribution occurring during EMT induced by epidermal growth factor in breast cancer MDA-MB-468 cells.
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| Overall design |
Analysis of 9 samples: (i)Input DNA to normalize samples; (ii) H3K9me2 Immunoprecipitated in untreated cells and (iii) H3K9me2 immunoprecipitated in EGF-treated cells. Experiment was performed in 3 independent biological replicates.
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| Contributor(s) |
Sindikubwabo F, Servant N, Baulande S, Raphael R |
| Citation(s) |
32747755 |
| |
| Submission date |
Oct 23, 2018 |
| Last update date |
Jul 09, 2021 |
| Contact name |
Nicolas Servant |
| E-mail(s) |
[email protected]
|
| Organization name |
Institut Curie
|
| Street address |
26 rue d'ulm
|
| City |
Paris Cedex 05 |
| ZIP/Postal code |
75248 |
| Country |
France |
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| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
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| Samples (22)
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| This SubSeries is part of SuperSeries: |
| GSE121664 |
Role of iron in the regulation of the epithelial-to-mesenchymal transition |
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| Relations |
| BioProject |
PRJNA498059 |
| SRA |
SRP166453 |
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