|
| Status |
Public on Oct 01, 2018 |
| Title |
ATO treatment on mesenchymal stem cells (MSCs) interacting breast cancer cells |
| Organisms |
Homo sapiens; Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Based on next generation RNA-seq, we examed Arsenic trioxide treatment (ATO) effect on MSCs-interacting MCF7 cells in 3D cultures. We found gap junction protein Cx43 is dramatically downregulated after ATO treatment..
|
| |
|
| Overall design |
human breast cancer cell line MCF-7 cells cocultured with mouse MSCs in 3D culture, with or without ATO treatment, are subject to NGS and then analyzed.
|
| |
|
| Contributor(s) |
Xiang Z, Hai W |
| Citation(s) |
30423299 |
| |
| Submission date |
Aug 22, 2018 |
| Last update date |
Feb 27, 2019 |
| Contact name |
Hai Wang |
| E-mail(s) |
[email protected]
|
| Organization name |
Roswell Park Cancer Institute
|
| Department |
Molecular and Cellular Biology
|
| Lab |
Hai Wang
|
| Street address |
Elm and Carlton Streets, MRC 328
|
| City |
Buffalo |
| State/province |
NY |
| ZIP/Postal code |
14263 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL19415 |
Illumina NextSeq 500 (Homo sapiens; Mus musculus) |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA487341 |
| SRA |
SRP158607 |
Less...
More...