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Status |
Public on Aug 23, 2018 |
Title |
Differentially expressed genes in normal gastric mucosa and gastric cancer tissues |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
To identify the differentially expressed genes in normal gastric mucosa and gastric cancer tissues, we employed the microarray profiling analysis. Genes with greater than 2-fold change and P-value <0.05 were identified as differentially expressed genes. From this dataset, we obtained differentially expressed genes by cluster analysis and enriched GOs was identified by Gene set enrichment analysis (GSEA) analysis, microtubule GO was one of the most enriched GOs, and the gene KIF14 was selected to go on to the next step in the study.
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Overall design |
10 paired of total samples were analyzed. Genes with an FDR 0.25 and a fold-change ≥2 were selected. Pathway and GO analysis was used for the next step analysis.
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Contributor(s) |
Yang Z, Gu Q |
Citation(s) |
30404039 |
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Submission date |
Aug 22, 2018 |
Last update date |
Jan 27, 2021 |
Contact name |
Zhongyin Yang |
E-mail(s) |
[email protected]
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Organization name |
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
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Department |
Department of Surgery
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Street address |
NO.197 Ruijin er road
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City |
Shanghai |
ZIP/Postal code |
200025 |
Country |
China |
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Platforms (1) |
GPL16686 |
[HuGene-2_0-st] Affymetrix Human Gene 2.0 ST Array [transcript (gene) version] |
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Samples (20)
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Relations |
BioProject |
PRJNA487176 |