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| Status |
Public on Nov 04, 2019 |
| Title |
The Msn2/4-like gene transcription factor Com2 (ORF YER130) is a key player of S. cerevisiae response and tolerance to sulphur dioxide |
| Platform organisms |
Schizosaccharomyces pombe; Saccharomyces cerevisiae |
| Sample organism |
Saccharomyces cerevisiae |
| Experiment type |
Expression profiling by array
|
| Summary |
Sulphur dioxide (SO2) and its derivatives are widely used as preservatives in food and beverage industries to assure the maintenance of microbiological quality of their products. In this work it is shown, for the first time, the essential role played by the transcriptional regulator Com (ORF YER130c) in S. cerevisiae response and tolerance to SO2, this being the first biological function attributed for this regulator.
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| Overall design |
Cells of S. cerevisiae BY4741 and of the mutant BY4741_∆com2 were cultivated in MMB growth medium (at pH 3.5) either or not supplemented with 0.5mM of sulphur dioxide. For RNA extraction, cells were collected at 60 min of incubation.
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| |
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| Contributor(s) |
Mendes-Ferreira A |
| Citation(s) |
31799324 |
| |
| Submission date |
Jul 30, 2018 |
| Last update date |
Dec 09, 2019 |
| Contact name |
Ana Mendes-Ferreira |
| E-mail(s) |
[email protected]
|
| Phone |
+351259350550
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| Organization name |
Universidade de Trás-os-Montes e Alto Douro
|
| Street address |
Quinta de Prados
|
| City |
Vila Real |
| ZIP/Postal code |
5000-801 |
| Country |
Portugal |
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| Platforms (1) |
| GPL2529 |
[Yeast_2] Affymetrix Yeast Genome 2.0 Array |
|
| Samples (12)
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| GSM3314453 |
S. cerevisiae_∆com2_Control 60min_ biological rep1 |
| GSM3314454 |
S. cerevisiae_∆com2_Control 60min_ biological rep2 |
| GSM3314455 |
S. cerevisiae_∆com2_Control 60min_ biological rep3 |
| GSM3314456 |
S. cerevisiae_∆com2_SO2 60min_ biological rep1 |
| GSM3314457 |
S. cerevisiae_∆com2_SO2 60min_ biological rep2 |
| GSM3314458 |
S. cerevisiae_∆com2_SO2 60min_ biological rep3 |
| GSM3314459 |
S. cerevisiae_BY4741_Control 60min_ biological rep1 |
| GSM3314460 |
S. cerevisiae_BY4741_Control 60min_ biological rep2 |
| GSM3314461 |
S. cerevisiae_BY4741_Control 60min_ biological rep3 |
| GSM3314462 |
S. cerevisiae_BY4741_SO2 60min_ biological rep1 |
| GSM3314463 |
S. cerevisiae_BY4741_SO2 60min_ biological rep2 |
| GSM3314464 |
S. cerevisiae_BY4741_SO2 60min_ biological rep3 |
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| Relations |
| BioProject |
PRJNA483481 |
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