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| Status |
Public on Mar 23, 2021 |
| Title |
RNA-seq of NOTCH1 mutation in chronic lymphocytic leukemia cell BaF3. |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
The hotspot c.7541_7542delCT NOTCH1 mutation has been proven to have a unfavorable clinical impact in chronic lymphocytic leukemia (CLL). The aim of our study was to investigate the influence of NOTCH1 mutation(c.7541_7542delCT) on NOTCH1 signaling in CLL cells using Gene Expression Profiling.
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| |
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| Overall design |
Examination of mRNA profiles of NOTCH1 genes in BaF3 cells transfected by pmax-Clover/pmax-Clover-ICN/pmax-Clover-ICN mut plasmids.
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| |
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| Contributor(s) |
Wang S, Liu H, Xu Z |
| Citation(s) |
31341237 |
| |
| Submission date |
Jun 13, 2018 |
| Last update date |
Mar 23, 2021 |
| Contact name |
Maolin Ge |
| E-mail(s) |
[email protected]
|
| Phone |
8577578190
|
| Organization name |
Harvard Medical School
|
| Department |
MGH Cancer Center
|
| Lab |
Bar-Peled
|
| Street address |
149 13th Street
|
| City |
Charlestown |
| State/province |
Massachusetts |
| ZIP/Postal code |
02129 |
| Country |
USA |
| |
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| Platforms (1) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA475876 |
| SRA |
SRP150407 |
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