|
| Status |
Public on Sep 06, 2018 |
| Title |
LSD1 regulates the plasmablast transcriptome |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To understand the role of LSD1 in B cell differentiation, mice with B cell conditional deletion of LSD1 were intravenously inoculated with LPS. After 3 days, B220+GL7-CD138- naïve B cells and CD138+ plasmablasts were FACS-sorted from the spleens and RNA-seq was performed to identify LSD1-target regulated genes.
|
| |
|
| Overall design |
RNA-seq on control or LSD1-deficient murine naïve B cells or plasmablasts.
|
| |
|
| Contributor(s) |
Haines RR, Scharer CD, Boss JM |
| Citation(s) |
30232138 |
| |
| Submission date |
May 22, 2018 |
| Last update date |
Mar 21, 2019 |
| Contact name |
Jeremy Matthew Boss |
| E-mail(s) |
[email protected]
|
| Organization name |
Emory University
|
| Department |
Microbiology and Immunology
|
| Lab |
Dr. Jeremy M. Boss
|
| Street address |
1510 Clifton Rd NE, Room 3120
|
| City |
Atlanta |
| State/province |
Georgia |
| ZIP/Postal code |
30322 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
| Samples (12)
|
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| This SubSeries is part of SuperSeries: |
| GSE114777 |
LSD1 regulates plasmablast chromatin accessibility and transcriptome |
|
| Relations |
| BioProject |
PRJNA472602 |
| SRA |
SRP148688 |
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