|
| Status |
Public on Feb 21, 2018 |
| Title |
miRNA expression of gefitinib-resistant cell lines |
| Organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by array
|
| Summary |
To identify novel miRNAs involved in acquired EGFR TKI resistance in NSCLC, genome-wide miRNA expression analysis was performed in gefitinib-resistant sub-cell lines and gefitinib-sensitive parental cell lines.
|
| |
|
| Overall design |
Gefitinib-resistant sub-cell lines were generated by growing gefitinib-sensitive EGFR-mutant NSCLC cell lines (PC9 and HCC827) in increasing concentrations of gefitinib to a final concentration of 10 uM up to 6 months.
|
| |
|
| Contributor(s) |
Lu X, Hongzhuan C |
| Citation(s) |
29717264 |
| |
| Submission date |
Feb 20, 2018 |
| Last update date |
May 23, 2018 |
| Contact name |
Lu Xu |
| E-mail(s) |
[email protected]
|
| Phone |
86-18621688913
|
| Organization name |
Shanghai Jiao Tong University, School of Medicine
|
| Department |
Pharmacology
|
| Street address |
280 South Chongqing Rd
|
| City |
Shanghai |
| ZIP/Postal code |
212000 |
| Country |
China |
| |
|
| Platforms (1) |
| GPL18402 |
Agilent-046064 Unrestricted_Human_miRNA_V19.0_Microarray (miRNA ID version) |
|
| Samples (4)
|
|
| Relations |
| BioProject |
PRJNA434645 |
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