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| Status |
Public on Feb 06, 2018 |
| Title |
Gene expression profile of SoNar-high and SoNar-low B-cell acute lymphoblastic leukemia (B-ALL) cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
To dissect the metabolic state of B-ALL cells, we have developed a genetically encoded fluorescent sensor (SoNar) for tracking cytosolic NADH and NAD+ redox states and constructed the transgenic mouse. Based on the NADH/NAD+ ratio, we have sorted SoNar-high and SoNar-low B-ALL cells to employ whole genome microarray expression profiling as a discovery platform to identify genes with the potential to regulate the metabolism of B-ALL cells.
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| Overall design |
SoNar-high and SoNar-low two population B-ALL cells from bone marrow were sorted to measure gene expression.
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| Contributor(s) |
Zheng J, Chen C |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Feb 05, 2018 |
| Last update date |
Feb 12, 2018 |
| Contact name |
Hao Gu |
| E-mail(s) |
[email protected]
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| Phone |
+86-13817406065
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| Organization name |
Shanghai Jiao Tong University School of Medicine
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| Street address |
280 South Chongqing Road, Shanghai
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| City |
Shanghai |
| ZIP/Postal code |
200025 |
| Country |
China |
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| Platforms (1) |
| GPL11202 |
Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Probe Name version) |
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| Samples (2) |
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| This SubSeries is part of SuperSeries: |
| GSE110112 |
Gene expression profile of SoNar-high and SoNar-low fetal liver blood cells and B-cell acute lymphoblastic leukemia (B-ALL) cells |
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| Relations |
| BioProject |
PRJNA432909 |
