|
| Status |
Public on Feb 06, 2018 |
| Title |
Gene expression profile of SoNar-high and SoNar-low fetal liver blood cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
To dissect the metabolic state of fetal liver HSCs, we have developed a genetically encoded fluorescent sensor (SoNar) for tracking cytosolic NADH and NAD+ redox states and constructed the transgenic mouse. Based on the NADH/NAD+ ratio, we have sorted SoNar-high and SoNar-low fetal liver blood cells to employ whole genome microarray expression profiling as a discovery platform to identify genes with the potential to regulate fetal liver HSC metabolism.
|
| |
|
| Overall design |
SoNar-high and SoNar-low two population blood cells from E13.5 fetal liver were sorted to measure gene expression.
|
| |
|
| Contributor(s) |
Zheng J, Gu H |
| Citation(s) |
32396938 |
| |
| Submission date |
Feb 05, 2018 |
| Last update date |
Aug 24, 2020 |
| Contact name |
Hao Gu |
| E-mail(s) |
[email protected]
|
| Phone |
+86-13817406065
|
| Organization name |
Shanghai Jiao Tong University School of Medicine
|
| Street address |
280 South Chongqing Road, Shanghai
|
| City |
Shanghai |
| ZIP/Postal code |
200025 |
| Country |
China |
| |
|
| Platforms (1) |
| GPL11202 |
Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Probe Name version) |
|
| Samples (2) |
|
| This SubSeries is part of SuperSeries: |
| GSE110112 |
Gene expression profile of SoNar-high and SoNar-low fetal liver blood cells and B-cell acute lymphoblastic leukemia (B-ALL) cells |
|
| Relations |
| BioProject |
PRJNA432907 |
