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Series GSE108593 Query DataSets for GSE108593
Status Public on Jan 01, 2020
Title Hyaluronic Acid Synthase-2 (HAS2) overexpression and deficiency effect on hepatic stellate cells
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Analysis of hepatic stellate cells (HSCs) isoltaed from ASMA-HAS2 transgenic and HSC-specific Has2 knockout mice. HAS2 synthesized hyaluronic acid, one of major extracellular matrix. Results provide insight into the role of HAS2 in hepatic stellate cells.
 
Overall design Hepatic stellate cell mRNA profiles of ASMA-HAS2 transgenic (Tg) and Has2 f/f Lrat-cre (KO) mice were generated by deep sequencing, in triplicate, using BGISEQ-500
 
Contributor(s) Yang YM, Deng N, Liu Z, Seki E
Citation(s) 31189722
NIH grant(s)
Grant ID Grant title Affiliation Name
R01 DK085252 Extracellular Matrix Regulates Hepatic Stellate Cell Activation and Fibrosis CEDARS-SINAI MEDICAL CENTER EKIHIRO SEKI
Submission date Dec 28, 2017
Last update date Apr 01, 2020
Contact name Yoon Mee Yang
E-mail(s) [email protected]
Organization name Kangwon National University
Department Pharmacy
Street address 1 Kangwondaehak-gil
City Chuncheon-si
State/province Gangwon-do
ZIP/Postal code 24341
Country South Korea
 
Platforms (1)
GPL23479 BGISEQ-500 (Mus musculus)
Samples (6)
GSM2905681 Day1_Tg4
GSM2905682 Day1_Tg5
GSM2905683 Day1_Tg6
Relations
BioProject PRJNA427766
SRA SRP127652

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE108593_RAW.tar 1.4 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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