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| Status |
Public on Feb 05, 2018 |
| Title |
Next Generation Sequencing Facilitates Quantitative Analysis of Health donors and SLE patients' PBMC Transcriptomes |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goals of this study are to compare SLE patients to Health donors PBMCs-derived transcriptome profiling (RNA-seq) to microarray and quantitative reverse transcription polymerase chain reaction (qRT–PCR) methods and to discovery the potential pathway which can be used as a therapeutic target.
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| Overall design |
Methods: Peripheral blood from Health donors and SLE patients with high or low peli1 expression was collected，PBMCs was processed to RNA-sequencing.
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| Contributor(s) |
Liu J, Xiao Y |
| Citation(s) |
29555915 |
| |
| Submission date |
Jul 14, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Junli Liu |
| E-mail(s) |
[email protected]
|
| Organization name |
Institute of Health Sciences Shanghai Institutes for Biological Sciences Chinese Academy of Sciences
|
| Street address |
New Research Buliding,320 Yue Yang Road Shanghai, P.R.China
|
| City |
上海 |
| ZIP/Postal code |
200031 |
| Country |
China |
| |
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| Platforms (1) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA394225 |
| SRA |
SRP111941 |
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