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    LOC127272823 H3K4me1 hESC enhancer GRCh37_chr2:24623030-24623530 [ Homo sapiens (human) ]

    Gene ID: 127272823, updated on 12-Sep-2024

    Summary

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    Gene symbol
    LOC127272823
    Gene description
    H3K4me1 hESC enhancer GRCh37_chr2:24623030-24623530
    Gene type
    biological region
    Feature type(s)
    regulatory: enhancer
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Oct 2022]
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    Genomic context

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    See LOC127272823 in Genome Data Viewer
    Location:
    chromosome: 2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (24400161..24400661)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (24434813..24435313)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (24623030..24623530)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene intersectin 2 Neighboring gene ribosomal protein L36a pseudogene 13 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11229 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11230 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11231 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15432 Neighboring gene high mobility group nucleosomal binding domain 2 pseudogene 20 Neighboring gene Sharpr-MPRA regulatory region 9937 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:24625737-24626243 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:24625230-24625736 Neighboring gene uncharacterized LOC105374329 Neighboring gene NANOG hESC enhancer GRCh37_chr2:24679828-24680425 Neighboring gene CRISPRi-validated cis-regulatory element chr2.904 Neighboring gene Sharpr-MPRA regulatory region 4589 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11232 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:24714093-24714251 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11233 Neighboring gene nuclear receptor coactivator 1 Neighboring gene MPRA-validated peak3621 silencer Neighboring gene RNA, 5S ribosomal pseudogene 88

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See Variation Viewer (GRCh37.p13)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_094674.1 

      Range
      101..601
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      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

      Range
      24400161..24400661
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060926.1 Alternate T2T-CHM13v2.0

      Range
      24434813..24435313
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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