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    SCGB3A2 secretoglobin family 3A member 2 [ Homo sapiens (human) ]

    Gene ID: 117156, updated on 27-Nov-2024

    Summary

    Official Symbol
    SCGB3A2provided by HGNC
    Official Full Name
    secretoglobin family 3A member 2provided by HGNC
    Primary source
    HGNC:HGNC:18391
    See related
    Ensembl:ENSG00000164265 MIM:606531; AllianceGenome:HGNC:18391
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    LU103; PNSP1; UGRP1; pnSP-1
    Summary
    The protein encoded by this gene is a secreted lung surfactant protein and a downstream target of thyroid transcription factor. A single nucleotide polymorphism in the promoter of this gene results in susceptibility to asthma.[provided by RefSeq, Mar 2010]
    Expression
    Restricted expression toward lung (RPKM 220.9) See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See SCGB3A2 in Genome Data Viewer
    Location:
    5q32
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (147878711..147882191)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (148414414..148417894)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (147258274..147261754)

    Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124901101 Neighboring gene serine peptidase inhibitor Kazal type 1 Neighboring gene formyl peptide receptor 1 pseudogene Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:147244599-147245140 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr5:147247772-147248437 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:147248438-147249104 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:147249105-147249771 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:147249772-147250438 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:147253107-147253772 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr5:147253773-147254440 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr5:147254441-147255106 Neighboring gene chromosome 5 open reading frame 46 Neighboring gene eukaryotic translation elongation factor 1 gamma pseudogene 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    secretoglobin family 3A member 2
    Names
    pneumo secretory protein 1
    uteroglobin-related protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_016867.1 RefSeqGene

      Range
      5001..8481
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_054023.5NP_473364.1  secretoglobin family 3A member 2 precursor

      See identical proteins and their annotated locations for NP_473364.1

      Status: REVIEWED

      Source sequence(s)
      AA988559, BC024232
      Consensus CDS
      CCDS4287.1
      UniProtKB/Swiss-Prot
      Q96PL1
      UniProtKB/TrEMBL
      Q2L6B3
      Related
      ENSP00000296694.4, ENST00000296694.5

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

      Range
      147878711..147882191
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060929.1 Alternate T2T-CHM13v2.0

      Range
      148414414..148417894
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)