| SETDB1 targeting SESN2 regulates mitochondrial damage and oxidative stress in renal ischemia-reperfusion injury. | SETDB1 targeting SESN2 regulates mitochondrial damage and oxidative stress in renal ischemia-reperfusion injury.
Xia K, Hui Y, Zhang L, Qiu Q, Zhong J, Chen H, Liu X, Wang L, Chen Z., Free PMC Article | 10/25/2024 |
| SETDB1 deletion causes DNA demethylation and upregulation of multiple zinc-finger genes. | SETDB1 deletion causes DNA demethylation and upregulation of multiple zinc-finger genes.
Kang YK, Eom J, Min B, Park JS., Free PMC Article | 06/30/2024 |
| [Downregulation of SETDB1 suppresses epithelial mesenchymal transition and invasion and metastasis in oral cancer via SOX7 methylation]. | [Downregulation of SETDB1 suppresses epithelial mesenchymal transition and invasion and metastasis in oral cancer via SOX7 methylation].
Hao Y, Bai XY, Huo F, Chen XB. | 04/10/2024 |
| Structural evidence for protein-protein interaction between the non-canonical methyl-CpG-binding domain of SETDB proteins and C11orf46. | Structural evidence for protein-protein interaction between the non-canonical methyl-CpG-binding domain of SETDB proteins and C11orf46.
Mahana Y, Ariyoshi M, Nozawa RS, Shibata S, Nagao K, Obuse C, Shirakawa M. | 03/14/2024 |
| SETDB1 promotes progression through upregulation of SF3B4 expression and regulates the immunity in ovarian cancer. | SETDB1 promotes progression through upregulation of SF3B4 expression and regulates the immunity in ovarian cancer.
Yang H, Sui L, Cai C, Chu H, Diao Y., Free PMC Article | 03/11/2024 |
| Cytoplasmic localization of SETDB1-induced Warburg effect via c-MYC-LDHA axis enhances migration and invasion in breast carcinoma. | Cytoplasmic localization of SETDB1‑induced Warburg effect via c‑MYC‑LDHA axis enhances migration and invasion in breast carcinoma.
Yang W, Wei Y, Wang T, Xu Y, Jin X, Qian H, Yang S, He S., Free PMC Article | 03/5/2024 |
| Hyperglycaemia aggravates periodontal inflamm-aging by promoting SETDB1-mediated LINE-1 de-repression in macrophages. | Hyperglycaemia aggravates periodontal inflamm-aging by promoting SETDB1-mediated LINE-1 de-repression in macrophages.
Yue Z, Nie L, Ji N, Sun Y, Zhu K, Zou H, Song X, Chen J, Wang Q. | 02/15/2024 |
| [Histone methyltransferases and regenerative myogenesis: A focus on SETDB1]. | [Histone methyltransferases and regenerative myogenesis: A focus on SETDB1].
Garcia P, Le Grand F. | 11/30/2023 |
| Evidence of a synthetic lethality interaction between SETDB1 histone methyltransferase and CHD4 chromatin remodeling protein in a triple negative breast cancer cell line. | Evidence of a synthetic lethality interaction between SETDB1 histone methyltransferase and CHD4 chromatin remodeling protein in a triple negative breast cancer cell line.
Moraes-Almeida MS, Sogayar MC, Demasi MAA., Free PMC Article | 11/21/2023 |
| SETDB1: A perspective into immune cell function and cancer immunotherapy. | SETDB1: A perspective into immune cell function and cancer immunotherapy.
Johnson E, Salari K, Yang S., Free PMC Article | 10/23/2023 |
| SETDB1 Methylates MCT1 Promoting Tumor Progression by Enhancing the Lactate Shuttle. | SETDB1 Methylates MCT1 Promoting Tumor Progression by Enhancing the Lactate Shuttle.
She X, Wu Q, Rao Z, Song D, Huang C, Feng S, Liu A, Liu L, Wan K, Li X, Yu C, Qiu C, Luo X, Hu J, Wang G, Xu F, Sun L., Free PMC Article | 10/10/2023 |
| Children with Chronic Immune Thrombocytopenia Exhibit High Expression of Human Endogenous Retroviruses TRIM28 and SETDB1. | Children with Chronic Immune Thrombocytopenia Exhibit High Expression of Human Endogenous Retroviruses TRIM28 and SETDB1.
Tovo PA, Galliano I, Parodi E, Calvi C, Gambarino S, Licciardi F, Dini M, Montanari P, Branca M, Ramenghi U, Bergallo M., Free PMC Article | 08/30/2023 |
| SETDB1 tumour suppressor roles in near-haploid mesothelioma involve TP53. | SETDB1 tumour suppressor roles in near-haploid mesothelioma involve TP53.
Xu M, Tu Y, Bi W, Lundberg MZ, Klooster I, Fletcher JA, Ou WB., Free PMC Article | 08/10/2023 |
| Histone methyltransferase SETDB1 promotes osteogenic differentiation in osteoporosis by activating OTX2-mediated BMP-Smad and Wnt/beta-catenin pathways. | Histone methyltransferase SETDB1 promotes osteogenic differentiation in osteoporosis by activating OTX2-mediated BMP-Smad and Wnt/β-catenin pathways.
Hu L, Cheng Z, Wu L, Luo L, Pan P, Li S, Jia Q, Yang N, Xu B. | 06/28/2023 |
| Epigenetic inhibition of lncRNA GMDS-AS1 by methyltransferase ESET promoted cell viability and metastasis of hepatocellular carcinoma. | Epigenetic inhibition of lncRNA GMDS-AS1 by methyltransferase ESET promoted cell viability and metastasis of hepatocellular carcinoma.
Huang J, Zhong T, Li G, Wang S, Qin R. | 05/24/2023 |
| Histone H3K9 methyltransferase SETDB1 overexpression correlates with pediatric high-grade gliomas progression and prognosis. | Histone H3K9 methyltransferase SETDB1 overexpression correlates with pediatric high-grade gliomas progression and prognosis.
Klonou A, Korkolopoulou P, Giannopoulou AI, Kanakoglou DS, Pampalou A, Gargalionis AN, Sarantis P, Mitsios A, Sgouros S, Papavassiliou AG, Piperi C. | 04/14/2023 |
| Pregnancy Is Associated with Impaired Transcription of Human Endogenous Retroviruses and of TRIM28 and SETDB1, Particularly in Mothers Affected by Multiple Sclerosis. | Pregnancy Is Associated with Impaired Transcription of Human Endogenous Retroviruses and of TRIM28 and SETDB1, Particularly in Mothers Affected by Multiple Sclerosis.
Tovo PA, Marozio L, Abbona G, Calvi C, Frezet F, Gambarino S, Dini M, Benedetto C, Galliano I, Bergallo M., Free PMC Article | 04/6/2023 |
| SETDB1 Modulates Degradation of Phosphorylated RB and Anticancer Efficacy of CDK4/6 Inhibitors. | SETDB1 Modulates Degradation of Phosphorylated RB and Anticancer Efficacy of CDK4/6 Inhibitors.
Huang Z, Li X, Tang B, Li H, Zhang J, Sun R, Ma J, Pan Y, Yan B, Zhou Y, Ding D, Yan Y, Jimenez R, Orme JJ, Jin X, Yang J, Huang H, Jia Z. | 03/17/2023 |
| Coordinated regulation of microRNA genes in C19MC by SETDB1. | Coordinated regulation of microRNA genes in C19MC by SETDB1.
Jeon K, Eom J, Min B, Park JS, Kang YK. | 12/10/2022 |
| SETDB1 fuels the lung cancer phenotype by modulating epigenome, 3D genome organization and chromatin mechanical properties. | SETDB1 fuels the lung cancer phenotype by modulating epigenome, 3D genome organization and chromatin mechanical properties.
Zakharova VV, Magnitov MD, Del Maestro L, Ulianov SV, Glentis A, Uyanik B, Williart A, Karpukhina A, Demidov O, Joliot V, Vassetzky YS, Mège RM, Piel M, Razin SV, Ait-Si-Ali S., Free PMC Article | 11/19/2022 |
| TRAF4 Promotes the Proliferation of Glioblastoma by Stabilizing SETDB1 to Activate the AKT Pathway. | TRAF4 Promotes the Proliferation of Glioblastoma by Stabilizing SETDB1 to Activate the AKT Pathway.
Gu H, Zhu S, Peng C, Wei Z, Shen Y, Yuan C, Yang H, Cui H, Yang L., Free PMC Article | 09/17/2022 |
| SETDB1 Restrains Endogenous Retrovirus Expression and Antitumor Immunity during Radiotherapy. | SETDB1 Restrains Endogenous Retrovirus Expression and Antitumor Immunity during Radiotherapy.
Pan D, Bao X, Hu M, Jiao M, Li F, Li CY., Free PMC Article | 08/13/2022 |
| Histone H3K9 methyltransferase SETDB1 augments invadopodia formation to promote tumor metastasis. | Histone H3K9 methyltransferase SETDB1 augments invadopodia formation to promote tumor metastasis.
Ueshima S, Fang J., Free PMC Article | 06/25/2022 |
| Enhanced Expression of Human Endogenous Retroviruses, TRIM28 and SETDB1 in Autism Spectrum Disorder. | Enhanced Expression of Human Endogenous Retroviruses, TRIM28 and SETDB1 in Autism Spectrum Disorder.
Tovo PA, Davico C, Marcotulli D, Vitiello B, Daprà V, Calvi C, Montanari P, Carpino A, Galliano I, Bergallo M., Free PMC Article | 06/18/2022 |
| Increased Expression of SETDB1 Predicts Poor Prognosis in Multiple Myeloma. | Increased Expression of SETDB1 Predicts Poor Prognosis in Multiple Myeloma.
Xiang J, Chen X, Chen M, Hou J., Free PMC Article | 04/16/2022 |