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    CD151 CD151 molecule (Raph blood group) [ Homo sapiens (human) ]

    Gene ID: 977, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    INHIBITION OF INTEGRIN VLA-3 AND TETRASPANIN CD151 PROTECTS AGAINST NEUTROPHIL-MEDIATED ENDOTHELIAL DAMAGE.

    INHIBITION OF INTEGRIN VLA-3 AND TETRASPANIN CD151 PROTECTS AGAINST NEUTROPHIL-MEDIATED ENDOTHELIAL DAMAGE.
    Ciambella C, Witt H, Dickinson CM, Smith ML, Coburn N, Messina N, Heffernan DS, Kim M, Reichner JS.,

    08/15/2024
    CD151 Maintains Endolysosomal Protein Quality to Inhibit Vascular Inflammation.

    CD151 Maintains Endolysosomal Protein Quality to Inhibit Vascular Inflammation.
    Chen J, Ding Y, Jiang C, Qu R, Wren JD, Georgescu C, Wang X, Reuter DN, Liu B, Giles CB, Mayr CH, Schiller HB, Dai J, Stipp CS, Subramaniyan B, Wang J, Zuo H, Huang C, Fung KM, Rice HC, Sonnenberg A, Wu D, Walters MS, Zhao YY, Kanie T, Hays FA, Papin JF, Wang DW, Zhang XA.,

    06/5/2024
    CD151 expression marks atrial- and ventricular- differentiation from human induced pluripotent stem cells.

    CD151 expression marks atrial- and ventricular- differentiation from human induced pluripotent stem cells.
    Nakanishi-Koakutsu M, Miki K, Naka Y, Sasaki M, Wakimizu T, Napier SC, Okubo C, Narita M, Nishikawa M, Hata R, Chonabayashi K, Hotta A, Imahashi K, Nishimoto T, Yoshida Y., Free PMC Article

    03/4/2024
    CD151 and prostate cancer progression: A review of current literature.

    CD151 and prostate cancer progression: A review of current literature.
    Kang Z, Luo Y, Xiao E, Li Q, Wang L.

    07/21/2023
    Exploring the role of CD151 in the tumor immune microenvironment: Therapeutic and clinical perspectives.

    Exploring the role of CD151 in the tumor immune microenvironment: Therapeutic and clinical perspectives.
    Malla R, Marni R, Chakraborty A.

    05/22/2023
    Proteomic Landscape of Exosomes Reveals the Functional Contributions of CD151 in Triple-Negative Breast Cancer.

    Proteomic Landscape of Exosomes Reveals the Functional Contributions of CD151 in Triple-Negative Breast Cancer.
    Li S, Li X, Yang S, Pi H, Li Z, Yao P, Zhang Q, Wang Q, Shen P, Li X, Ji J., Free PMC Article

    03/26/2022
    CD151 promotes Colorectal Cancer progression by a crosstalk involving CEACAM6, LGR5 and Wnt signaling via TGFbeta1.

    CD151 promotes Colorectal Cancer progression by a crosstalk involving CEACAM6, LGR5 and Wnt signaling via TGFβ1.
    Yang T, Wang H, Li M, Yang L, Han Y, Liu C, Zhang B, Wu M, Wang G, Zhang Z, Zhang W, Huang J, Zhang H, Cao T, Chen P, Zhang W., Free PMC Article

    01/22/2022
    CD151 drives cancer progression depending on integrin alpha3beta1 through EGFR signaling in non-small cell lung cancer.

    CD151 drives cancer progression depending on integrin α3β1 through EGFR signaling in non-small cell lung cancer.
    Zhu J, Cai T, Zhou J, Du W, Zeng Y, Liu T, Fu Y, Li Y, Qian Q, Yang XH, Li Q, Huang JA, Liu Z., Free PMC Article

    01/1/2022
    circCD151 promotes GLI2 expression by regulating miR30d5p and enhancing proliferation, invasion and stemness of lung cancer.

    circCD151 promotes GLI2 expression by regulating miR‑30d‑5p and enhancing proliferation, invasion and stemness of lung cancer.
    Zhao L, Zheng H, Jiang P., Free PMC Article

    12/25/2021
    CD151 enrichment in exosomes of luminal androgen receptor breast cancer cell line contributes to cell invasion.

    CD151 enrichment in exosomes of luminal androgen receptor breast cancer cell line contributes to cell invasion.
    Li D, Lai W, Wang Q, Xiang Z, Nan X, Yang X, Fang Q.

    10/2/2021
    Key Role of CD151-integrin Complex in Lung Cancer Metastasis and Mechanisms Involved.

    Key Role of CD151-integrin Complex in Lung Cancer Metastasis and Mechanisms Involved.
    Peng D, Li PC, Liu T, Zeng HS, Fei YJ, Liu ZX, Zuo HJ.

    09/25/2021
    Downregulation of CD151 induces oxidative stress and apoptosis in trophoblast cells via inhibiting ERK/Nrf2 signaling pathway in preeclampsia.

    Downregulation of CD151 induces oxidative stress and apoptosis in trophoblast cells via inhibiting ERK/Nrf2 signaling pathway in preeclampsia.
    Wang Z, Cai B, Cao C, Lv H, Dai Y, Zheng M, Zhao G, Peng Y, Gou W, Wang J, Liu D, Hu Y.

    07/17/2021
    HPV caught in the tetraspanin web?

    HPV caught in the tetraspanin web?
    Finke J, Hitschler L, Boller K, Florin L, Lang T., Free PMC Article

    02/2/2021
    The tetraspanin CD151 marks a unique population of activated human T cells.

    The tetraspanin CD151 marks a unique population of activated human T cells.
    Perez MD, Seu L, Lowman KE, Moylan DC, Tidwell C, Samuel S, Duverger A, Wagner FH, Carlin E, Sharma V, Pope B, Raman C, Erdmann N, Locke J, Hu H, Sabbaj S, Kutsch O., Free PMC Article

    01/16/2021
    The CD151-midkine pathway regulates the immune microenvironment in inflammatory breast cancer.

    The CD151-midkine pathway regulates the immune microenvironment in inflammatory breast cancer.
    Hayward S, Gachehiladze M, Badr N, Andrijes R, Molostvov G, Paniushkina L, Sopikova B, Slobodová Z, Mgebrishvili G, Sharma N, Horimoto Y, Burg D, Robertson G, Hanby A, Hoar F, Rea D, Eckhardt BL, Ueno NT, Nazarenko I, Long HM, van Laere S, Shaaban AM, Berditchevski F.

    09/19/2020
    Findings provide new insights into the dynamic and complex regulation of adhesion structures in keratinocytes and the pathogenic mechanisms underlying skin blistering diseases caused by mutations in the gene for CD151.

    Tetraspanin CD151 and integrin α3β1 contribute to the stabilization of integrin α6β4-containing cell-matrix adhesions.
    Te Molder L, Juksar J, Harkes R, Wang W, Kreft M, Sonnenberg A.

    07/25/2020
    We find that the proteinase ADAM17 activates the extracellular signal-regulated kinases (ERK1/2) pathway by the shedding of growth factors which triggers the formation of an endocytic entry platform. Infectious endocytic entry platforms carrying virus particles consist of two-fold larger CD151 domains containing the EGFR. Our finding clearly dissects initial virus binding from ADAM17-dependent assembly of a HPV/CD151/EGFR

    ADAM17-dependent signaling is required for oncogenic human papillomavirus entry platform assembly.
    Mikuličić S, Finke J, Boukhallouk F, Wüstenhagen E, Sons D, Homsi Y, Reiss K, Lang T, Florin L., Free PMC Article

    02/29/2020
    CLP suppresses growth and migration by attenuating cell cycle of TNBC cell lines via EGFR and CD151 signaling.

    Marine natural compound cyclo(L-leucyl-L-prolyl) peptide inhibits migration of triple negative breast cancer cells by disrupting interaction of CD151 and EGFR signaling.
    Kgk D, Kumari S, G S, Malla RR.

    02/22/2020
    forced expression of SNHG3 promoted cell invasion, epithelial-mesenchymal transition (EMT), and sorafenib resistance in HCC. Moreover, SNHG3 overexpression induced HCC cells EMT via miR-128/CD151 cascade activation.

    LncRNA SNHG3 induces EMT and sorafenib resistance by modulating the miR-128/CD151 pathway in hepatocellular carcinoma.
    Zhang PF, Wang F, Wu J, Wu Y, Huang W, Liu D, Huang XY, Zhang XM, Ke AW.

    01/25/2020
    CD151 may promote the proliferation and invasion of breast cancer cells by regulating TGF-beta1/Smad pathway.

    CD151 promotes breast cancer metastasis by activating TGF-β1/Smad signaling pathway.
    Zhao SJ, Zhao HD, Li J, Zhang H, Gao DT, Wang Q.

    01/18/2020
    Results illustrate functional interdependency between CD151 complexes and FGFR2, and suggest a previously unsuspected role of CD151 in breast tumorigenesis.

    CD151 regulates expression of FGFR2 in breast cancer cells via PKC-dependent pathways.
    Sadej R, Lu X, Turczyk L, Novitskaya V, Lopez-Clavijo AF, Kordek R, Potemski P, Wakelam MJO, Romanska-Knight H, Berditchevski F.

    01/11/2020
    The expression of tetraspanins NET-6 and CD151 may indicate an alteration of their biological function during neoplastic transformation.

    Expression of tetraspanins NET-6 and CD151 in breast cancer as a potential tumor biomarker.
    Jiang L, Zhang X, Geradts J, Wei Q, Hochwald S, Xu H, Huang H.

    11/30/2019
    an involvement of CD151 in regulation of ErbB2/ErbB3 heterodimerization and its impact on cell response to Herceptin, is reported.

    Tetraspanin CD151 impairs heterodimerization of ErbB2/ErbB3 in breast cancer cells.
    Mieszkowska M, Piasecka D, Potemski P, Debska-Szmich S, Rychlowski M, Kordek R, Sadej R, Romanska HM.

    05/18/2019
    CD151 supports anti-cancer drug resistance independent of integrins.

    Integrin-independent support of cancer drug resistance by tetraspanin CD151.
    Hwang S, Takimoto T, Hemler ME., Free PMC Article

    04/27/2019
    CD151 promotes proliferation and migration of SK-NEP-1 cells through the GSK-3beta/P21/cyclinD signaling pathway in this study

    CD151 promotes proliferation and migration of SK-NEP-1 cells via the GSK-3β/P21/cyclinD signaling pathway.
    Wang J, Lei W, Li G, Ma H, Guo H, Li S.

    03/23/2019
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