| The heterogeneity of tumour immune microenvironment revealing the CRABP2/CD69 signature discriminates distinct clinical outcomes in breast cancer. | The heterogeneity of tumour immune microenvironment revealing the CRABP2/CD69 signature discriminates distinct clinical outcomes in breast cancer.
Mei J, Cai Y, Chen L, Wu Y, Liu J, Qian Z, Jiang Y, Zhang P, Xia T, Pan X, Zhang Y., Free PMC Article | 11/18/2023 |
| Cancer cell-derived CD69 induced under lipid and oxygen starvation promotes ovarian cancer progression through fibronectin. | Cancer cell-derived CD69 induced under lipid and oxygen starvation promotes ovarian cancer progression through fibronectin.
Koizume S, Kanayama T, Kimura Y, Hirano H, Takahashi T, Ota Y, Miyazaki K, Yoshihara M, Nakamura Y, Yokose T, Kato H, Takenaka K, Sato S, Tadokoro H, Miyagi E, Miyagi Y., Free PMC Article | 06/5/2023 |
| CD69 serves as a potential diagnostic and prognostic biomarker for hepatocellular carcinoma. | CD69 serves as a potential diagnostic and prognostic biomarker for hepatocellular carcinoma.
Tang K, Li X, Mo J, Chen Y, Huang C, Li T, Luo T, Zhong Z, Jiang Y, Yang D, Mo W., Free PMC Article | 05/13/2023 |
| Machine learning links different gene patterns of viral infection to immunosuppression and immune-related biomarkers in severe burns. | Machine learning links different gene patterns of viral infection to immunosuppression and immune-related biomarkers in severe burns.
Wang P, Zhang Z, Lin R, Lin J, Liu J, Zhou X, Jiang L, Wang Y, Deng X, Lai H, Xiao H., Free PMC Article | 12/24/2022 |
| Combined assessment of S- and N-specific IL-2 and IL-13 secretion and CD69 neo-expression for discrimination of post-infection and post-vaccination cellular SARS-CoV-2-specific immune response. | Combined assessment of S- and N-specific IL-2 and IL-13 secretion and CD69 neo-expression for discrimination of post-infection and post-vaccination cellular SARS-CoV-2-specific immune response.
Kratzer B, Schlax LC, Gattinger P, Waidhofer-Söllner P, Trapin D, Tauber PA, Sehgal ANA, Körmöczi U, Rottal A, Feichter M, Oberhofer T, Grabmeier-Pfistershammer K, Borochova K, Dorofeeva Y, Tulaeva I, Weber M, Mühl B, Kropfmüller A, Negrin B, Kundi M, Valenta R, Pickl WF., Free PMC Article | 11/5/2022 |
| CD4+ T cells in inflammatory diseases: pathogenic T-helper cells and the CD69-Myl9 system. | CD4+ T cells in inflammatory diseases: pathogenic T-helper cells and the CD69-Myl9 system.
Nakayama T, Hirahara K, Kimura MY, Iwamura C, Kiuchi M, Kokubo K, Onodera A, Hashimoto K, Motohashi S. | 03/26/2022 |
| Apoptosis inhibitor of macrophage as a biomarker for disease activity in Japanese children with IgA nephropathy and Henoch-Schonlein purpura nephritis. | Apoptosis inhibitor of macrophage as a biomarker for disease activity in Japanese children with IgA nephropathy and Henoch-Schönlein purpura nephritis.
Irabu H, Shimizu M, Kaneko S, Inoue N, Mizuta M, Tasaki Y, Ohta K, Yachie A, Wada T. | 01/15/2022 |
| Prognostic Relevance of Concordant Expression CD69 and CD56 in Response to Bortezomib Combination Therapy in Multiple Myeloma Patients. | Prognostic Relevance of Concordant Expression CD69 and CD56 in Response to Bortezomib Combination Therapy in Multiple Myeloma Patients.
ElMenshawy N, Farag NA, Atia DM, Abousamra N, Shahin D, Fawzi E, Ghazi H, El-Kott AF, Eissa M. | 10/2/2021 |
| T cells selectively filter oscillatory signals on the minutes timescale. | T cells selectively filter oscillatory signals on the minutes timescale.
O'Donoghue GP, Bugaj LJ, Anderson W, Daniels KG, Rawlings DJ, Lim WA., Free PMC Article | 08/7/2021 |
| Increased CD69 expression on activated eosinophils in eosinophilic chronic rhinosinusitis correlates with clinical findings. | Increased CD69 expression on activated eosinophils in eosinophilic chronic rhinosinusitis correlates with clinical findings.
Yun Y, Kanda A, Kobayashi Y, Van Bui D, Suzuki K, Sawada S, Baba K, Yagi M, Asako M, Okazaki H, Ikeda H, Kawamura S, Nakamura A, Dombrowicz D, Tomoda K, Iwai H. | 12/12/2020 |
| Oxidized low-density lipoprotein binding to CD69 confers a regulatory phenotype to human T cells, dampening Th17 responses and ameliorating atherosclerosis. | Oxidized Low-Density Lipoprotein Receptor in Lymphocytes Prevents Atherosclerosis and Predicts Subclinical Disease.
Tsilingiri K, de la Fuente H, Relaño M, Sánchez-Díaz R, Rodríguez C, Crespo J, Sánchez-Cabo F, Dopazo A, Alonso-Lebrero JL, Vara A, Vázquez J, Casasnovas JM, Alfonso F, Ibáñez B, Fuster V, Martínez-González J, Martín P, Sánchez-Madrid F. | 10/26/2019 |
| CD69 and CD24 partially inhibit apoptosis and erythroid differentiation in Chronic myeloid leukemia cells. | CD69 partially inhibits apoptosis and erythroid differentiation via CD24, and their knockdown increase imatinib sensitivity in BCR-ABL-positive cells.
Huang SY, Liu YH, Chen YJ, Yeh YY, Huang HM. | 10/5/2019 |
| In the presence of fusion protein-tyrosine kinases ITK-FER and ITK-SYK, signal transducer and activator of transcription 3 (STAT3) was highly phosphorylated and early activation antigen CD69 (CD69) was significantly elevated. | Translocation-generated ITK-FER and ITK-SYK fusions induce STAT3 phosphorylation and CD69 expression.
Fathi NN, Mohammad DK, Görgens A, Andaloussi SE, Zain R, Nore BF, Smith CIE. | 03/30/2019 |
| CD69(+) T cells were associated with disease recurrence. | Prognostic roles for IL-2-producing and CD69(+) T cell subsets in colorectal cancer patients.
Taylor ES, McCall JL, Shen S, Girardin A, Munro FM, Black MA, Ward-Hartstonge KA, Kemp RA. | 01/26/2019 |
| CD69 is a direct target of miR-367-3p. | Dysregulation of CD69 by overexpression of microRNA‑367‑3p associated with post‑myocardial infarction cardiac fibrosis.
Hu H, Li J, Zhang J. | 11/10/2018 |
| The frequency of CD69+ T cells was significantly higher in CD8+ and CD4+ T cells in nasal polyps compared with the peripheral blood of patients with chronic rhinosinusitis. | Accumulation of CD69+ tissue‑resident memory T cells in the nasal polyps of patients with chronic rhinosinusitis.
Ickrath P, Kleinsasser N, Ding X, Ginzkey C, Beyersdorf N, Hagen R, Kerkau T, Hackenberg S. | 10/13/2018 |
| this paper shows that decrease of CD69 levels on TCR Valpha7.2(+)CD4(+) innate-like lymphocytes is associated with impaired cytotoxic functions in chronic hepatitis B virus-infected patients | Decrease of CD69 levels on TCR Vα7.2(+)CD4(+) innate-like lymphocytes is associated with impaired cytotoxic functions in chronic hepatitis B virus-infected patients.
Yong YK, Tan HY, Saeidi A, Rosmawati M, Atiya N, Ansari AW, Rajarajeswaran J, Vadivelu J, Velu V, Larsson M, Shankar EM. | 04/14/2018 |
| AIM expression in the kidney was associated with urinary protein and decline in kidney function. | Association of apoptosis inhibitor of macrophage (AIM) expression with urinary protein and kidney dysfunction.
Oshima M, Iwata Y, Furuichi K, Sakai N, Shimizu M, Hara A, Kitajima S, Toyama T, Shinozaki Y, Sagara A, Umeda E, Kaneko S, Arai S, Miyazaki T, Wada T. | 06/24/2017 |
| Higher CD69 expression were less sensitive to bendamustine and is associated with chronic lymphocytic leukemia. | CD69 expression potentially predicts response to bendamustine and its modulation by ibrutinib or idelalisib enhances cytotoxic effect in chronic lymphocytic leukemia.
Montraveta A, Lee-Vergés E, Roldán J, Jiménez L, Cabezas S, Clot G, Pinyol M, Xargay-Torrent S, Rosich L, Arimany-Nardí C, Aymerich M, Villamor N, López-Guillermo A, Pérez-Galán P, Roué G, Pastor-Anglada M, Campo E, López-Guerra M, Colomer D., Free PMC Article | 12/17/2016 |
| In vitro functional assays showed that CD69(+) Treg cells exerted an important suppressive effect on the activation of T effector cells | Levels of regulatory T cells CD69(+)NKG2D(+)IL-10(+) are increased in patients with autoimmune thyroid disorders.
Rodríguez-Muñoz A, Vitales-Noyola M, Ramos-Levi A, Serrano-Somavilla A, González-Amaro R, Marazuela M. | 12/17/2016 |
| results demonstrate the functional and mechanistic interplays between CD69 and S100A8/S100A9 in supporting Treg-cell differentiation | Glycosylation-dependent interaction between CD69 and S100A8/S100A9 complex is required for regulatory T-cell differentiation.
Lin CR, Wei TY, Tsai HY, Wu YT, Wu PY, Chen ST. | 05/28/2016 |
| Elevated expression of CD69 and CD161 on NK cells can be considered as immunological risk markers in RSA and IVF failure. | Increase of CD69, CD161 and CD94 on NK cells in women with recurrent spontaneous abortion and in vitro fertilization failure.
Ghafourian M, Karami N, Khodadadi A, Nikbakht R. | 02/28/2015 |
| Human tumor-infiltrating CD4+CD69+ T cells suppress T cell proliferation via membarene -bound TGF-beta1. | Human hepatocellular carcinoma-infiltrating CD4⁺CD69⁺Foxp3⁻ regulatory T cell suppresses T cell response via membrane-bound TGF-β1.
Han Y, Yang Y, Chen Z, Jiang Z, Gu Y, Liu Y, Xu S, Lin C, Pan Z, Zhou W, Cao X. | 12/6/2014 |
| these findings identify CD69 and galectin-1 to be a novel regulatory receptor-ligand pair that modulates Th17 effector cell differentiation and function. | The leukocyte activation receptor CD69 controls T cell differentiation through its interaction with galectin-1.
de la Fuente H, Cruz-Adalia A, Martinez Del Hoyo G, Cibrián-Vera D, Bonay P, Pérez-Hernández D, Vázquez J, Navarro P, Gutierrez-Gallego R, Ramirez-Huesca M, Martín P, Sánchez-Madrid F., Free PMC Article | 08/9/2014 |
| REVIEW: CD69 exerts a complex immunoregulatory role in humans, and that it could be considered as a target molecule for the therapy of immune-mediated diseases | Is CD69 an effective brake to control inflammatory diseases?
González-Amaro R, Cortés JR, Sánchez-Madrid F, Martín P., Free PMC Article | 05/10/2014 |