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    WTAP WT1 associated protein [ Homo sapiens (human) ]

    Gene ID: 9589, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    WTAP-dependent N6-methyladenosine methylation of lncRNA TEX41 promotes renal cell carcinoma progression.

    WTAP-dependent N6-methyladenosine methylation of lncRNA TEX41 promotes renal cell carcinoma progression.
    Zhou Z, Chen X, Wang H, Ding L, Wang M, Li G, Xia L., Free PMC Article

    10/30/2024
    WTAP mediated m6A-modified circ_0056856 contributes to the proliferation, migration, and invasion of IL-22-stimulated human keratinocyte by miR-197-3p/CDK1 axis.

    WTAP mediated m6A-modified circ_0056856 contributes to the proliferation, migration, and invasion of IL-22-stimulated human keratinocyte by miR-197-3p/CDK1 axis.
    Du X, Shi L, Wang B, Zhang G.

    09/13/2024
    WTAP-Involved the m6A Modification of lncRNA FAM83H-AS1 Accelerates the Development of Gastric Cancer.

    WTAP-Involved the m6A Modification of lncRNA FAM83H-AS1 Accelerates the Development of Gastric Cancer.
    Liu N, Zhang C, Zhang L.

    09/4/2024
    WTAP-MEDIATED M6A MODIFICATION OF KLF6 AGGRAVATES HYPOXIA/REOXYGENATION-INDUCED HUMAN CARDIOMYOCYTE INJURY.

    WTAP-MEDIATED M6A MODIFICATION OF KLF6 AGGRAVATES HYPOXIA/REOXYGENATION-INDUCED HUMAN CARDIOMYOCYTE INJURY.
    Fang M, Li T, Wu Z.

    08/15/2024
    Elevated WTAP promotes hyperinflammation by increasing m6A modification in inflammatory disease models.

    Elevated WTAP promotes hyperinflammation by increasing m6A modification in inflammatory disease models.
    Ge Y, Chen R, Ling T, Liu B, Huang J, Cheng Y, Lin Y, Chen H, Xie X, Xia G, Luo G, Yuan S, Xu A., Free PMC Article

    08/4/2024
    WTAP promotes proliferation of esophageal squamous cell carcinoma via m[6]A-dependent epigenetic promoting of PTP4A1.

    WTAP promotes proliferation of esophageal squamous cell carcinoma via m(6)A-dependent epigenetic promoting of PTP4A1.
    Zou J, Ma Q, Gao C, Yang M, Wen J, Xu L, Guo X, Zhong X, Duan Y., Free PMC Article

    07/15/2024
    WTAP-Mediated N6-Methyladenosine of RNAs Facilitate the Pathophysiology of Atopic Dermatitis.

    WTAP-Mediated N6-Methyladenosine of RNAs Facilitate the Pathophysiology of Atopic Dermatitis.
    Tan L, Chen X, Yan S, Guo A, Gao L, Zhou L, Zhou Y, Zeng J, Lu J.

    05/7/2024
    WTAP enhances the instability of SYTL1 mRNA caused by YTHDF2 in bladder cancer.

    WTAP enhances the instability of SYTL1 mRNA caused by YTHDF2 in bladder cancer.
    Wang J, Luo J, Wu X, Li Z.

    04/26/2024
    WTAP Mediates NUPR1 Regulation of LCN2 Through m[6]A Modification to Influence Ferroptosis, Thereby Promoting Breast Cancer Proliferation, Migration and Invasion.

    WTAP Mediates NUPR1 Regulation of LCN2 Through m(6)A Modification to Influence Ferroptosis, Thereby Promoting Breast Cancer Proliferation, Migration and Invasion.
    Tan M, He Y, Yi J, Chen J, Guo Q, Liao N, Peng L.

    04/25/2024
    WTAP regulates the production of reactive oxygen species, promotes malignant progression, and is closely related to the tumor microenvironment in glioblastoma.

    WTAP regulates the production of reactive oxygen species, promotes malignant progression, and is closely related to the tumor microenvironment in glioblastoma.
    Ji Q, Guo Y, Li Z, Zhang X., Free PMC Article

    04/12/2024
    WTAP Mediated N6-methyladenosine RNA Modification of ELF3 Drives Cellular Senescence by Upregulating IRF8.

    WTAP Mediated N6-methyladenosine RNA Modification of ELF3 Drives Cellular Senescence by Upregulating IRF8.
    Zhou L, Zhong Y, Wang F, Guo Y, Mao R, Xie H, Zhang Y, Li J., Free PMC Article

    03/15/2024
    Regulation of ULK1 by WTAP/IGF2BP3 axis enhances mitophagy and progression in epithelial ovarian cancer.

    Regulation of ULK1 by WTAP/IGF2BP3 axis enhances mitophagy and progression in epithelial ovarian cancer.
    Wang J, Zheng F, Wang D, Yang Q., Free PMC Article

    02/21/2024
    WTAP-mediated m[6]A modification of FRZB triggers the inflammatory response via the Wnt signaling pathway in osteoarthritis.

    WTAP-mediated m(6)A modification of FRZB triggers the inflammatory response via the Wnt signaling pathway in osteoarthritis.
    An X, Wang R, Lv Z, Wu W, Sun Z, Wu R, Yan W, Jiang Q, Xu X., Free PMC Article

    02/12/2024
    [m[6]A methylase WTAP participates in renal ischemia-reperfusion injury by regulating FOXO1 expression].

    [m(6)A methylase WTAP participates in renal ischemia-reperfusion injury by regulating FOXO1 expression].
    Zhao G, Li H, Zhang H, Xiao K, Yang H, Li Z, Fu C., Free PMC Article

    01/10/2024
    WTAP Mediated the N6-methyladenosine Modification of PDK4 to Regulate the Malignant Behaviors of Colorectal Cancer Cells In Vitro and In Vivo.

    WTAP Mediated the N6-methyladenosine Modification of PDK4 to Regulate the Malignant Behaviors of Colorectal Cancer Cells In Vitro and In Vivo.
    Dai X, Chen K, Xie Y.

    08/24/2023
    A cleaved METTL3 potentiates the METTL3-WTAP interaction and breast cancer progression.

    A cleaved METTL3 potentiates the METTL3-WTAP interaction and breast cancer progression.
    Yan C, Xiong J, Zhou Z, Li Q, Gao C, Zhang M, Yu L, Li J, Hu MM, Zhang CS, Cai C, Zhang H, Zhang J., Free PMC Article

    08/19/2023
    N6-methyladenosine (m6A) methyltransferase WTAP-mediated miR-92b-5p accelerates osteoarthritis progression.

    N6-methyladenosine (m6A) methyltransferase WTAP-mediated miR-92b-5p accelerates osteoarthritis progression.
    Lin Z, Jiang T, Zheng W, Zhang J, Li A, Lu C, Liu W., Free PMC Article

    08/16/2023
    PRMT1 methylation of WTAP promotes multiple myeloma tumorigenesis by activating oxidative phosphorylation via m6A modification of NDUFS6.

    PRMT1 methylation of WTAP promotes multiple myeloma tumorigenesis by activating oxidative phosphorylation via m6A modification of NDUFS6.
    Jia Y, Yu X, Liu R, Shi L, Jin H, Yang D, Zhang X, Shen Y, Feng Y, Zhang P, Yang Y, Zhang L, Zhang P, Li Z, He A, Kong G., Free PMC Article

    08/11/2023
    WTAP activates MAPK signaling through m6A methylation in VEGFA mRNA-mediated by YTHDC1 to promote colorectal cancer development.

    WTAP activates MAPK signaling through m6A methylation in VEGFA mRNA-mediated by YTHDC1 to promote colorectal cancer development.
    Ye M, Chen J, Yu P, Hu C, Wang B, Bao J, Lu F, Zhong Y, Yan L, Kan J, Bai J, Tian Y, Tang Q.

    07/14/2023
    The differences in biological behavior and gene expression characteristics between pure and mixed early gastric signet ring cell carcinomas.

    The differences in biological behavior and gene expression characteristics between pure and mixed early gastric signet ring cell carcinomas.
    Wang X, Li X, Yang P, Qin X, Yu J, Cheng Y, Zhang G, Tang L.

    06/28/2023
    HIF1alpha-mediated transactivation of WTAP promotes AML cell proliferation via m[6]A-dependent stabilization of KDM4B mRNA.

    HIF1α-mediated transactivation of WTAP promotes AML cell proliferation via m(6)A-dependent stabilization of KDM4B mRNA.
    Shao YL, Li YQ, Li MY, Wang LL, Zhou HS, Liu DH, Yu L, Lin J, Gao XN.

    06/13/2023
    High expression of WTAP is related to poor prognosis in nasopharyngeal carcinoma.

    High expression of WTAP is related to poor prognosis in nasopharyngeal carcinoma.
    Tao CJ, Zhang P, Chen YY, Chen M.

    05/28/2023
    WTAP-Mediated m6A RNA Methylation Regulates the Differentiation of Bone Marrow Mesenchymal Stem Cells via the miR-29b-3p/HDAC4 Axis.

    WTAP-Mediated m6A RNA Methylation Regulates the Differentiation of Bone Marrow Mesenchymal Stem Cells via the miR-29b-3p/HDAC4 Axis.
    Liu J, You Y, Sun Z, Zhang L, Li X, Dai Z, Ma J, Chen Y, Jiao G., Free PMC Article

    05/17/2023
    m6A Methyltransferase, WTAP, Promotes Cancer Progression in Laryngeal Squamous Cell Carcinoma by Regulating PLAU Stability.

    m6A Methyltransferase, WTAP, Promotes Cancer Progression in Laryngeal Squamous Cell Carcinoma by Regulating PLAU Stability.
    Liu F, Xia F, Wang C, Ren R, Zhang M, Gong J, Zhang Q.

    04/26/2023
    m6A writer WTAP targets NRF2 to accelerate bladder cancer malignancy via m6A-dependent ferroptosis regulation.

    m6A writer WTAP targets NRF2 to accelerate bladder cancer malignancy via m6A-dependent ferroptosis regulation.
    Wang K, Wang G, Li G, Zhang W, Wang Y, Lin X, Han C, Chen H, Shi L, Reheman A, Li J, Li Z, Yang X.

    04/21/2023
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