Interactions between DksA and Stress-Responsive Alternative Sigma Factors Control Inorganic Polyphosphate Accumulation in Escherichia coli. | Interactions between DksA and Stress-Responsive Alternative Sigma Factors Control Inorganic Polyphosphate Accumulation in Escherichia coli. Gray MJ., Free PMC Article | 02/13/2021 |
DNA melting is an active process initiated in closed promoter complex (RPc) and that the RNAP conformations of intermediates are significantly different from that of RPc and open promoter complex. | Structures of RNA Polymerase Closed and Intermediate Complexes Reveal Mechanisms of DNA Opening and Transcription Initiation. Glyde R, Ye F, Darbari VC, Zhang N, Buck M, Zhang X., Free PMC Article | 09/30/2017 |
Upregulation of fliZ by NtrC-sigma(N) was shown to be indirect and required an intact flagellar regulator flhDC. | σ(N) -dependent control of acid resistance and the locus of enterocyte effacement in enterohemorrhagic Escherichia coli is activated by acetyl phosphate in a manner requiring flagellar regulator FlhDC and the σ(S) antagonist FliZ. Mitra A, Fay PA, Vendura KW, Alla Z, Carroll RK, Shaw LN, Riordan JT., Free PMC Article | 04/11/2015 |
Data suggest a direct binding mechanism, in which sigma(54)RNA polymerase (rpoN) reaches the local vicinity of promoters by 3D diffusion. | RNA polymerase approaches its promoter without long-range sliding along DNA. Friedman LJ, Mumm JP, Gelles J., Free PMC Article | 08/31/2013 |
Expression of the flagellar sigma(F) factor (FliA), another sigma(70) family protein, is controlled positively by RpoN but negatively by RpoS. | Antagonistic regulation of motility and transcriptome expression by RpoN and RpoS in Escherichia coli. Dong T, Yu R, Schellhorn H. | 04/23/2011 |
These observations suggest a novel mechanism for negative regulation in bacterial enhancer binding proteins such as NorR in which the GAF domain targets the sigma(54)-interaction surface to prevent access of the AAA+ domain to the sigma factor. | Nitric oxide-responsive interdomain regulation targets the σ54-interaction surface in the enhancer binding protein NorR. Bush M, Ghosh T, Tucker N, Zhang X, Dixon R., Free PMC Article | 02/26/2011 |
Results inidicate that there are 70 sigma(54) promoters in total in the entire Escherichia coli genome. | Promoter and regulon analysis of nitrogen assimilation factor, sigma54, reveal alternative strategy for E. coli MG1655 flagellar biosynthesis. Zhao K, Liu M, Burgess RR., Free PMC Article | 04/12/2010 |
Analyses of promoter mutants obtained by in vitro chemical mutagenesis of the atoDAEB promoter verified both the importance of AtoC binding for the inducibility of the promoter by acetoacetate and the sigma54 dependence of atoDAEB expression. | Interactions of the antizyme AtoC with regulatory elements of the Escherichia coli atoDAEB operon. Matta MK, Lioliou EE, Panagiotidis CH, Kyriakidis DA, Panagiotidis CA., Free PMC Article | 01/21/2010 |
Identified as new member of the polyamine modulon together with Cra and H-NS. | Enhancement of the synthesis of RpoN, Cra, and H-NS by polyamines at the level of translation in Escherichia coli cultured with glucose and glutamate. Terui Y, Higashi K, Taniguchi S, Shigemasa A, Nishimura K, Yamamoto K, Kashiwagi K, Ishihama A, Igarashi K., Free PMC Article | 01/21/2010 |
We propose a passive model for ppGpp/DksA regulation of sigma54-dependent transcription that depends on the potent negative effects of these regulatory molecules on transcription from powerful stringently regulated sigma70 promoters. | The guanosine tetraphosphate (ppGpp) alarmone, DksA and promoter affinity for RNA polymerase in regulation of sigma-dependent transcription. Bernardo LM, Johansson LU, Solera D, Skärfstad E, Shingler V. | 01/21/2010 |
ppGpp and its co-factor DksA have roles in controlling transcription dependent on sigma54 | Properties of RNA polymerase bypass mutants: implications for the role of ppGpp and its co-factor DksA in controlling transcription dependent on sigma54. Szalewska-Palasz A, Johansson LUM, Bernardo LMD, Skärfstad E, Stec E, Brännström K, Shingler V. | 01/21/2010 |