| miR-520f-3p blocks MNNG-induced gastric precancerous lesions via the KLF7/NFkappaB pathway. | miR-520f-3p blocks MNNG-induced gastric precancerous lesions via the KLF7/NFκB pathway.
Jiang W, Lu W, Liu J, Ren H, Zhao X, Yang W. | 02/15/2024 |
| KLF7 promotes adipocyte inflammation and glucose metabolism disorder by activating the PKCzeta/NF-kappaB pathway. | KLF7 promotes adipocyte inflammation and glucose metabolism disorder by activating the PKCζ/NF-κB pathway.
Yang X, Liang M, Tang Y, Ma D, Li M, Yuan C, Hou Y, Sun C, Liu J, Wei Q, Chang Y, Wang C, Zhang J. | 06/26/2023 |
| The KLF7/PFKL/ACADL axis modulates cardiac metabolic remodelling during cardiac hypertrophy in male mice. | The KLF7/PFKL/ACADL axis modulates cardiac metabolic remodelling during cardiac hypertrophy in male mice.
Wang C, Qiao S, Zhao Y, Tian H, Yan W, Hou X, Wang R, Zhang B, Yang C, Zhu F, Jiao Y, Jin J, Chen Y, Tian W., Free PMC Article | 02/28/2023 |
| KLF7 Alleviates Atherosclerotic Lesions and Inhibits Glucose Metabolic Reprogramming in Macrophages by Regulating HDAC4/miR-148b-3p/NCOR1. | KLF7 Alleviates Atherosclerotic Lesions and Inhibits Glucose Metabolic Reprogramming in Macrophages by Regulating HDAC4/miR-148b-3p/NCOR1.
Chen F, Li J, Zheng T, Chen T, Yuan Z. | 10/29/2022 |
| Kruppel-like Transcription Factor 7 Is a Causal Gene in Autism Development. | Krüppel-like Transcription Factor 7 Is a Causal Gene in Autism Development.
Tian H, Qiao S, Zhao Y, Jin X, Wang C, Wang R, Wang Y, Jiao Y, Liu Y, Zhang B, Jin J, Chen Y, Jiang Q, Tian W., Free PMC Article | 04/16/2022 |
| Methylation of miR-19b-3p promoter exacerbates inflammatory responses in sepsis-induced ALI via targeting KLF7. | Methylation of miR-19b-3p promoter exacerbates inflammatory responses in sepsis-induced ALI via targeting KLF7.
Jiang L, Wang M, Sun R, Lin Z, Liu R, Cai H, Tang Z, Zhang R. | 12/25/2021 |
| MicroRNA-136-3p inhibits glioma tumorigenesis in vitro and in vivo by targeting KLF7. | MicroRNA-136-3p inhibits glioma tumorigenesis in vitro and in vivo by targeting KLF7.
Xu Y., Free PMC Article | 07/3/2021 |
| KLF7 promotes pancreatic cancer growth and metastasis by up-regulating ISG expression and maintaining Golgi complex integrity. | KLF7 promotes pancreatic cancer growth and metastasis by up-regulating ISG expression and maintaining Golgi complex integrity.
Gupta R, Malvi P, Parajuli KR, Janostiak R, Bugide S, Cai G, Zhu LJ, Green MR, Wajapeyee N., Free PMC Article | 09/5/2020 |
| KLF7 overexpression in bone marrow stromal stem cells graft transplantation promotes sciatic nerve regeneration. | KLF7 overexpression in bone marrow stromal stem cells graft transplantation promotes sciatic nerve regeneration.
Li WY, Zhu GY, Yue WJ, Sun GD, Zhu XF, Wang Y. | 08/29/2020 |
| Mechanistically, KLF7 transcriptionally activated argininosuccinate lyase (ASL), which was observed highly expressed in glioma tissues. KLF7 accelerates the xenografted tumor growth of glioma cells. KLF7 potentiates polyamine biosynthesis and glioma cell growth via transcriptionally activates ASL. | KLF7 promotes polyamine biosynthesis and glioma development through transcriptionally activating ASL.
Guan F, Kang Z, Zhang JT, Xue NN, Yin H, Wang L, Mao BB, Peng WC, Zhang BL, Liang X, Hu ZQ. | 06/27/2020 |
| Our findings suggest that KLF7 promotes DPSN axonal plasticity and the formation of synapses with motor neurons at the caudal spinal cord, leading to improved functional recovery | AAV-KLF7 Promotes Descending Propriospinal Neuron Axonal Plasticity after Spinal Cord Injury.
Li WY, Wang Y, Zhai FG, Sun P, Cheng YX, Deng LX, Wang ZY., Free PMC Article | 05/26/2018 |
| was upregulated in quiescent satellite cell and nonproliferating myoblasts. | KLF7 Regulates Satellite Cell Quiescence in Response to Extracellular Signaling.
Wang X, Shen QW, Wang J, Zhang Z, Feng F, Chen T, Zhang Y, Wei H, Li Z, Wang X, Wang Y. | 12/9/2017 |
| Data show that adult corticospinal tract (CST) neurons failed to up-regulate KLF7 in response to axon injury, and overexpression of VP16-KLF7 in vivo promoted both sprouting and regenerative axon growth in the CST of adult mice. | Krüppel-like Factor 7 engineered for transcriptional activation promotes axon regeneration in the adult corticospinal tract.
Blackmore MG, Wang Z, Lerch JK, Motti D, Zhang YP, Shields CB, Lee JK, Goldberg JL, Lemmon VP, Bixby JL., Free PMC Article | 08/18/2012 |
| lack of a KLF family member affects dopaminergic neuron development. | Krüppel-like factor 7 is required for olfactory bulb dopaminergic neuron development.
Caiazzo M, Colucci-D'Amato L, Volpicelli F, Speranza L, Petrone C, Pastore L, Stifani S, Ramirez F, Bellenchi GC, di Porzio U. | 03/12/2011 |
| KLF7 inactivation in Klf7-null mice decreases the expression of the neurogenic marker brain lipid-binding protein/fatty acid-binding protein 7 (BLBP/FABP7) in neural stem cells (NSCs). | Transcription factor KLF7 regulates differentiation of neuroectodermal and mesodermal cell lineages.
Caiazzo M, Colucci-D'Amato L, Esposito MT, Parisi S, Stifani S, Ramirez F, di Porzio U. | 08/9/2010 |
| Klf7 is important for neuronal morphogenesis in selected regions of the central nervous system. | Transcription factor KLF7 is important for neuronal morphogenesis in selected regions of the nervous system.
Laub F, Lei L, Sumiyoshi H, Kajimura D, Dragomir C, Smaldone S, Puche AC, Petros TJ, Mason C, Parada LF, Ramirez F., Free PMC Article | 01/21/2010 |
| Cooperation between Brn3a and Klf7 is required for endogenous TrkA gene expression and the survival of nociceptive sensory neurons. | Brn3a and Klf7 cooperate to control TrkA expression in sensory neurons.
Lei L, Zhou J, Lin L, Parada LF. | 01/21/2010 |
| mice without Kruppel-like factor 7 activity die at birth and display hypoplastic olfactory bulbs which lack peripheral innervation | Mice without transcription factor KLF7 provide new insight into olfactory bulb development.
Laub F, Dragomir C, Ramirez F. | 01/21/2010 |
| Upregulation of adiponectin protein by (-)-catechin may involve, at least in part, suppression of KLF7 in 3T3-L1 cells. | (-)-Catechin suppresses expression of Kruppel-like factor 7 and increases expression and secretion of adiponectin protein in 3T3-L1 cells.
Cho SY, Park PJ, Shin HJ, Kim YK, Shin DW, Shin ES, Lee HH, Lee BG, Baik JH, Lee TR. | 01/21/2010 |
| Results advance knowledge of transcriptional regulation of olfactory neurogenesis and KLF7 action. | Identification of genes regulated by transcription factor KLF7 in differentiating olfactory sensory neurons.
Kajimura D, Dragomir C, Ramirez F, Laub F. | 01/21/2010 |
| Klf7 gene ablation reduces TrkA expression in sensory neurons due to effect on cell death | The zinc finger transcription factor Klf7 is required for TrkA gene expression and development of nociceptive sensory neurons.
Lei L, Laub F, Lush M, Romero M, Zhou J, Luikart B, Klesse L, Ramirez F, Parada LF., Free PMC Article | 01/21/2010 |