Identification and validation of tryptophan-related gene signatures to predict prognosis and immunotherapy response in lung adenocarcinoma reveals a critical role for PTTG1.
Wang Z, Zhang J, Zuo C, Chen H, Wang L, Xie Y, Ma H, Min S, Wang X, Lian C., Free PMC Article

Multi-Omics Analysis of the Oncogenic Value of Pituitary Tumor-Transforming Gene 1 (PTTG1) in Human Cancers.
Wang L, Liu X.

Pituitary tumor transforming gene 1 promotes proliferation and malignant phenotype in osteosarcoma via NF-κB signaling.
Hu X, Yang F, Mei H.

SPTBN1 Mediates the Cytoplasmic Constraint of PTTG1, Impairing Its Oncogenic Activity in Human Seminoma.
Teveroni E, Di Nicuolo F, Vergani E, Oliva A, Vodola EP, Bianchetti G, Maulucci G, De Spirito M, Cenci T, Pierconti F, Gulino G, Iavarone F, Urbani A, Milardi D, Pontecorvi A, Mancini F., Free PMC Article

Phosphorylated PTTG1 switches its subcellular distribution and promotes β-catenin stabilization and subsequent transcription activity.
Zhang X, Wu N, Huang H, Li S, Liu S, Zhang R, Huang Y, Lyu H, Xiao S, Ali DW, Michalak M, Chen XZ, Zhou C, Tang J.

miR‑374c‑5p regulates PTTG1 and inhibits cell growth and metastasis in hepatocellular carcinoma by regulating epithelial‑mesenchymal transition.
Yang G, Xiog Y, Wang G, Li W, Tang T, Sun J, Li J., Free PMC Article

Clinical significance and potential regulatory mechanism of overexpression of pituitary tumor-transforming gene transcription factor in bladder cancer.
Li JD, Farah AA, Huang ZG, Zhai GQ, Wang RG, Liu JL, Wang QJ, Zhang GL, Lei ZL, Dang YW, Li SH., Free PMC Article

SIRT1 suppresses pituitary tumor progression by downregulating PTTG1 expression.
Huang J, Zhang F, Hu G, Pan Y, Sun W, Jiang L, Wang P, Qiu J, Ding X.

The pituitary tumour-transforming gene 1/delta-like homologue 1 pathway plays a key role in liver fibrogenesis.
Perramón M, Carvajal S, Reichenbach V, Fernández-Varo G, Boix L, Macias-Muñoz L, Melgar-Lesmes P, Bruix J, Melmed S, Lamas S, Jiménez W., Free PMC Article

miR-362-3p suppresses sinonasal squamous cell carcinoma progression via directly targeting pituitary tumor-transforming gene 1.
Meng Z, Zhu S, Liu N, Tian J.

Identification of hub genes associated with prognosis, diagnosis, immune infiltration and therapeutic drug in liver cancer by integrated analysis.
Lei X, Zhang M, Guan B, Chen Q, Dong Z, Wang C., Free PMC Article

Signatures of Multi-Omics Reveal Distinct Tumor Immune Microenvironment Contributing to Immunotherapy in Lung Adenocarcinoma.
Huang Z, Li B, Guo Y, Wu L, Kou F, Yang L., Free PMC Article

[Dysregulation of MAD2L1/CAMK2A/PTTG1 Gene Cluster Maintains the Stemness Characteristics of Uterine Corpus Endometrial Carcinoma].
Zheng J, Zhang YW, Pan ZF.

KLF10 inhibits cell growth by regulating PTTG1 in multiple myeloma under the regulation of microRNA-106b-5p.
Zhou M, Chen J, Zhang H, Liu H, Yao H, Wang X, Zhang W, Zhao Y, Yang N., Free PMC Article

Structural basis of human separase regulation by securin and CDK1-cyclin B1.
Yu J, Raia P, Ghent CM, Raisch T, Sadian Y, Cavadini S, Sabale PM, Barford D, Raunser S, Morgan DO, Boland A., Free PMC Article

Gene signatures and prognostic analyses of the Tob/BTG pituitary tumor-transforming gene (PTTG) family in clinical breast cancer patients.
Wu CC, Ekanem TI, Phan NN, Loan DTT, Hou SY, Lee KH, Wang CY., Free PMC Article

CDC20 and PTTG1 are Important Biomarkers and Potential Therapeutic Targets for Metastatic Prostate Cancer.
Dai L, Song ZX, Wei DP, Zhang JD, Liang JQ, Wang BB, Ma WT, Li LY, Dang YL, Zhao L, Zhang LM, Zhao YM.

Suppression of PTTG1 inhibits cell angiogenesis, migration and invasion in glioma cells.
Cui L, Ren T, Zhao H, Chen S, Zheng M, Gao X, Feng D, Yang L, Jin X, Zhuo R.

Upregulation of PTTG1 is associated with poor prognosis in prostate cancer.
Fraune C, Yehorov S, Luebke AM, Steurer S, Hube-Magg C, Büscheck F, Höflmayer D, Tsourlakis MC, Clauditz TS, Simon R, Sauter G, Weidemann S, Dum D, Kind S, Minner S, Schlomm T, Huland H, Heinzer H, Graefen M, Burandt E.

The lncRNA PTTG3P promotes the progression of CRPC via upregulating PTTG1.
Huang S, Liao Q, Li W, Deng G, Jia M, Fang Q, Ji H, Meng M.

Alteration of Pituitary Tumor Transforming Gene 1 by MicroRNA-186 and 655 Regulates Invasion Ability of Human Oral Squamous Cell Carcinoma.
Lee SS, Choi JH, Lim SM, Kim GJ, Lee SK, Jeon YK., Free PMC Article

[MiR-300 inhibits invasion and metastasis of osteosarcoma cell MG63 by negatively regulating PTTG1].
Liang D, Wu X, Bai J, Zhang L, Yin C, Zhong W., Free PMC Article

aarF domain containing kinase 5 gene promotes invasion and migration of lung cancer cells through ADCK5-SOX9-PTTG1 pathway.
Qiu M, Li G, Wang P, Li X, Lai F, Luo R, Liu B, Lin J.

Validation of the OncoMasTR Risk Score in Estrogen Receptor-Positive/HER2-Negative Patients: A TransATAC study.
Buus R, Sestak I, Barron S, Loughman T, Fender B, Ruiz CL, Dynoodt P, Wang CA, O'Leary D, Gallagher WM, Dowsett M, Cuzick J.

[Expression of pituitary tumor-transforming gene-1 and its pathogenic role in systemic sclerosis].
Yang A, Huang Y, Zhang Y, Yang K, Wang J, Liu Q., Free PMC Article