| Loss of KLF15 impairs endometrial receptivity by inhibiting EMT in endometriosis. | Loss of KLF15 impairs endometrial receptivity by inhibiting EMT in endometriosis.
Huang Y, Wang Z, Li B, Ke L, Xiong Y, Zhang Y., Free PMC Article | 05/1/2024 |
| [KLF15/mTOR related proteins involved in effect of aerobic interval training on improving skeletal muscle lesions in rats with type 2 diabetes]. | [KLF15/mTOR related proteins involved in effect of aerobic interval training on improving skeletal muscle lesions in rats with type 2 diabetes].
Liao ZX, Huang L, Zhu HZ, Zhu MJ. | 06/15/2023 |
| Krupsilonppel-like factor 15 suppresses renal glomerular mesangial cell proliferation via enhancing P53 SUMO1 conjugation. | Krϋppel-like factor 15 suppresses renal glomerular mesangial cell proliferation via enhancing P53 SUMO1 conjugation.
Wu L, Li O, Zhu F, Wang X, Chen P, Cai G, Chen X, Hong Q., Free PMC Article | 10/2/2021 |
| MiR-137-3p exacerbates the ischemia-reperfusion injured cardiomyocyte apoptosis by targeting KLF15. | MiR-137-3p exacerbates the ischemia-reperfusion injured cardiomyocyte apoptosis by targeting KLF15.
Zhao T, Qiu Z, Gao Y. | 06/5/2021 |
| Loss of cardiac KLF15 in chronic kidney disease induced left ventricular hypertrophy, is associated with trophic and fibrotic signaling. | Left ventricular hypertrophy in experimental chronic kidney disease is associated with reduced expression of cardiac Kruppel-like factor 15.
Patel SK, Velkoska E, Gayed D, Ramchand J, Lesmana J, Burrell LM., Free PMC Article | 05/25/2019 |
| Angiotensin II stimulation of transforming growth factor beta expression in the myocytes activated p38alpha kinase via TAK1 kinase, inhibiting KLF15 expression. | Estrogen receptor beta maintains expression of KLF15 to prevent cardiac myocyte hypertrophy in female rodents.
Hoa N, Ge L, Korach KS, Levin ER., Free PMC Article | 03/23/2019 |
| Ang II down-regulates KLF15 expression via the AT1 receptor, and KLF15 is likely to inhibit Ang II-induced CTGF expression by repressing the recruitment of the co-activator P/CAF to the CTGF promoter. | KLF 15 Works as an Early Anti-Fibrotic Transcriptional Regulator in Ang II-Induced Renal Fibrosis via Down-Regulation of CTGF Expression.
Gu X, Xu D, Fu L, Wang Y, Mei C, Gao X. | 09/1/2018 |
| Overexpression of KLF15 can partially rescue aortic remodeling and aortic dissection formation in animal models by inhibiting CTGF expression. | KLF15 Overexpression Protects β-Aminopropionitrile-Induced Aortic Rupture in Rodent Model via Inhibiting Connective Tissue Growth Factor.
Zhan B, Hu Z, Chen J, Zhu R, Zhao H, Yang J, Zhang Z, Nie R. | 07/22/2017 |
| Resveratrol treatment induces KLF15 expression, which may, in part, explain its therapeutic efficacy to improve the cardiac phenotype following ischemic injury. | Resveratrol-Mediated Expression of KLF15 in the Ischemic Myocardium is Associated with an Improved Cardiac Phenotype.
Rogers RG, Otis JS. | 03/25/2017 |
| KLF15 is repressed after pressure overload and induces fibrotic changes in the heart. | KLF15 is an essential negative regulatory factor for the cardiac remodeling response to pressure overload.
Yu Y, Ma J, Xiao Y, Yang Q, Kang H, Zhen J, Yu L, Chen L. | 11/28/2015 |
| upregulation of KLF15 expression in myocardial fibroblasts might promote vascular generation, alleviate the myocardial interstitial fibrosis and improve cardiac function in this pressure overload rat model | [Impacts and mechanisms of kruppel like factor 15 in pressure overload induced cardiac remodeling and angiogenesis in rats].
Yu Y, Zou S, Ma J, Chen L. | 11/21/2015 |
| KLF15 plays an important role in renal interstitial fibrosis through regulation of ERK/MAPK and JNK/MAPK signal pathways. | Kruppel-like factor 15 modulates renal interstitial fibrosis by ERK/MAPK and JNK/MAPK pathways regulation.
Gao X, Wu G, Gu X, Fu L, Mei C. | 08/30/2014 |
| KLF15 as a key regulator of myocardial lipid utilization and is the first to implicate the KLF transcription factor family in cardiac metabolism. | Kruppel-like factor 15 is a critical regulator of cardiac lipid metabolism.
Prosdocimo DA, Anand P, Liao X, Zhu H, Shelkay S, Artero-Calderon P, Zhang L, Kirsh J, Moore D, Rosca MG, Vazquez E, Kerner J, Akat KM, Williams Z, Zhao J, Fujioka H, Tuschl T, Bai X, Schulze PC, Hoppel CL, Jain MK, Haldar SM., Free PMC Article | 04/26/2014 |
| KLF15 may be a useful target for therapeutic intervention in mesangial proliferative glomerulonephritis | Kruppel-like factor-15 inhibits the proliferation of mesangial cells.
Hong Q, Li C, Xie Y, Lv Y, Liu X, Shi S, Ding R, Zhang X, Zhang L, Liu S, Chen X. | 11/17/2012 |
| Regulation of cardiac gene expression by KLF15, a repressor of myocardin activity. | Regulation of cardiac gene expression by KLF15, a repressor of myocardin activity.
Leenders JJ, Wijnen WJ, Hiller M, van der Made I, Lentink V, van Leeuwen REW, Herias V, Pokharel S, Heymans S, de Windt LJ, Høydal MA, Pinto YM, Creemers EE., Free PMC Article | 09/20/2010 |
| The present results indicated that miR-133 regulates the expression of GLUT4 by targeting KLF15 and is involved in metabolic control in cardiomyocytes. | MicroRNA-133 regulates the expression of GLUT4 by targeting KLF15 and is involved in metabolic control in cardiac myocytes.
Horie T, Ono K, Nishi H, Iwanaga Y, Nagao K, Kinoshita M, Kuwabara Y, Takanabe R, Hasegawa K, Kita T, Kimura T. | 01/21/2010 |
| These studies identify KLF15 as part of a heretofore unrecognized pathway regulating the cardiac response to hemodynamic stress | Kruppel-like factor 15 is a regulator of cardiomyocyte hypertrophy.
Fisch S, Gray S, Heymans S, Haldar SM, Wang B, Pfister O, Cui L, Kumar A, Lin Z, Sen-Banerjee S, Das H, Petersen CA, Mende U, Burleigh BA, Zhu Y, Pinto YM, Liao R, Jain MK., Free PMC Article | 01/21/2010 |
| together with the trans-activation of the AceCS2 promoter, it is suggested that fasting-induced AceCS2 expression is largely contributed by KLF15 | A Kruppel-like factor KLF15 contributes fasting-induced transcriptional activation of mitochondrial acetyl-CoA synthetase gene AceCS2.
Yamamoto J, Ikeda Y, Iguchi H, Fujino T, Tanaka T, Asaba H, Iwasaki S, Ioka RX, Kaneko IW, Magoori K, Takahashi S, Mori T, Sakaue H, Kodama T, Yanagisawa M, Yamamoto TT, Ito S, Sakai J. | 01/21/2010 |