| Interaction Between HCN and Slack Channels Regulates mPFC Pyramidal Cell Excitability in Working Memory Circuits. | Interaction Between HCN and Slack Channels Regulates mPFC Pyramidal Cell Excitability in Working Memory Circuits.
Wu J, El-Hassar L, Datta D, Thomas M, Zhang Y, Jenkins DP, DeLuca NJ, Chatterjee M, Gribkoff VK, Arnsten AFT, Kaczmarek LK. | 04/1/2024 |
| Histamine depolarizes projection neurons but not interneurons in the cerebellar nuclei via the hyperpolarization-activated cyclic nucleotide-gated (HCN) channels coupled to histamine H2 receptors. | Selective Modulation of Histaminergic Inputs on Projection Neurons of Cerebellum Rapidly Promotes Motor Coordination via HCN Channels.
Zhang J, Zhuang QX, Li B, Wu GY, Yung WH, Zhu JN, Wang JJ. | 12/17/2016 |
| Insulin receptor (IR), an integral membrane protein, directly phosphorylates the CNGA1 subunit of CNG channels that in turn affects the function of these channels negatively. CNGA1 is a direct substrate of IR. | Insulin receptor regulates photoreceptor CNG channel activity.
Gupta VK, Rajala A, Rajala RV., Free PMC Article | 02/9/2013 |
| estrogen and progesterone act in renal tissues modulating CNG-A1 and Na/K ATPase gene expression | Role of estrogen and progesterone in the modulation of CNG-A1 and Na/K+-ATPase expression in the renal cortex.
Gracelli JB, Souza-Menezes J, Barbosa CM, Ornellas FS, Takiya CM, Alves LM, Wengert M, Feltran Gda S, Caruso-Neves C, Moyses MR, Prota LF, Morales MM. | 10/27/2012 |
| Data demonstrate that CNGA1 is expressed in rat cerebellar granule cells and forms functional channels. | Functional cGMP-gated channels in cerebellar granule cells.
Lopez-Jimenez ME, González JC, Lizasoain I, Sánchez-Prieto J, Hernández-Guijo JM, Torres M. | 04/7/2012 |
| Data show robust CNGA1 (but not CNGA2 or CNGA3) channel expression principally in rat alveolar type I cells and suggest that CNGA1 channels mediate cGMP-stimulated, amiloride-insensitive, lung liquid absorption. | Alveolar epithelial CNGA1 channels mediate cGMP-stimulated, amiloride-insensitive, lung liquid absorption.
Wilkinson WJ, Benjamin AR, De Proost I, Orogo-Wenn MC, Yamazaki Y, Staub O, Morita T, Adriaensen D, Riccardi D, Walters DV, Kemp PJ. | 12/3/2011 |
| Grb14 is a normal physiological modulator of CNG channel function in vivo. | Growth factor receptor-bound protein 14: a new modulator of photoreceptor-specific cyclic-nucleotide-gated channel.
Gupta VK, Rajala A, Daly RJ, Rajala RV., Free PMC Article | 02/5/2011 |
| suggest a potential role for HCN channels in regulation of glucagon secretion via modulating Ca(2+) and Na(+) channel activities | Presence of functional hyperpolarisation-activated cyclic nucleotide-gated channels in clonal alpha cell lines and rat islet alpha cells.
Zhang Y, Zhang N, Gyulkhandanyan AV, Xu E, Gaisano HY, Wheeler MB, Wang Q. | 01/21/2010 |
| Our data imply that HCN-expressing GABAergic neurons provide rhythmic drive in all phases of the hippocampal theta activity. | The presence of pacemaker HCN channels identifies theta rhythmic GABAergic neurons in the medial septum.
Varga V, Hangya B, Kránitz K, Ludányi A, Zemankovics R, Katona I, Shigemoto R, Freund TF, Borhegyi Z., Free PMC Article | 01/21/2010 |
| Cyclic nucleotide-gated channels (CNG1 and CNG2 A subunits) affect membrane potential and excitability of rat medial vestibular nucleus. | Functional role of cyclic nucleotide-gated channels in rat medial vestibular nucleus neurons.
Podda MV, D'Ascenzo M, Leone L, Piacentini R, Azzena GB, Grassi C., Free PMC Article | 01/21/2010 |
| Transcripts for a functional CNG ion channel exist in the cochlea resulting from combinations of CNG2 with CNG5 and CNG4.3. CNG2 and CNG5 immunoreactivity in hair cell stereocilia suggests a role for cAMP-sensitive CNG channels in signal transduction. | Expression of subunits for the cAMP-sensitive 'olfactory' cyclic nucleotide-gated ion channel in the cochlea: implications for signal transduction.
Drescher MJ, Barretto RL, Chaturvedi D, Beisel KW, Hatfield JS, Khan KM, Drescher DG. | 01/21/2010 |
| CNG channels switch on and off the olfactory signaling pathway, and that the on and off signals may both be amplified by the subsequent olfactory signaling steps. | Odorant inhibition of the olfactory cyclic nucleotide-gated channel with a native molecular assembly.
Chen TY, Takeuchi H, Kurahashi T., Free PMC Article | 01/21/2010 |
| NO activates the olfactory cyclic nucleotide-gated conductance independent from cGMP in isolated rat olfactory receptor neurons. | NO activates the olfactory cyclic nucleotide-gated conductance independent from cGMP in isolated rat olfactory receptor neurons.
Schmachtenberg O, Diaz J, Bacigalupo J. | 01/21/2010 |
| expression of the alpha-subunit of rod- and olfactory-type CNG channels (CNG1 and CNG2, respectively) in the rat medial vestibular nucleus | Expression of cyclic nucleotide-gated channels in the rat medial vestibular nucleus.
Podda MV, Marcocci ME, Del Carlo B, Palamara AT, Azzena GB, Grassi C. | 01/21/2010 |