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    HAVCR2 hepatitis A virus cellular receptor 2 [ Homo sapiens (human) ]

    Gene ID: 84868, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    TOX2 nuclear-cytosol translocation is linked to leukemogenesis of acute T-cell leukemia by repressing TIM3 transcription.

    TOX2 nuclear-cytosol translocation is linked to leukemogenesis of acute T-cell leukemia by repressing TIM3 transcription.
    Li A, Zhang J, Zhan L, Liu X, Zeng X, Zhu Q, Wang Z, Li J., Free PMC Article

    11/7/2024
    T-Cell Immunoglobulin and Mucin Domain 3 (TIM-3) Gene Expression as a Negative Biomarker of B-Cell Acute Lymphoblastic Leukemia.

    T-Cell Immunoglobulin and Mucin Domain 3 (TIM-3) Gene Expression as a Negative Biomarker of B-Cell Acute Lymphoblastic Leukemia.
    Basingab FS, Bashanfer M, Alrofaidi AA, Barefah AS, Hammad R, Alahdal HM, Alrahimi JS, Zaher KA, Hassan S, Algiraigri AH, El-Daly MM, Alkarim SA, Aldahlawi AM., Free PMC Article

    11/4/2024
    TIM-3/Galectin-9 and CD160 expression in salivary adenoid cystic carcinoma.

    TIM-3/Galectin-9 and CD160 expression in salivary adenoid cystic carcinoma.
    Li M, Wan ZX, Tang YY, Liang XH, Tang YL.

    09/24/2024
    Pan-cancer analysis of TIM-3 transcriptomic expression reveals high levels in pancreatic cancer and interpatient heterogeneity.

    Pan-cancer analysis of TIM-3 transcriptomic expression reveals high levels in pancreatic cancer and interpatient heterogeneity.
    Lim J, Kurzrock R, Nishizaki D, Miyashita H, Adashek JJ, Lee S, Pabla S, Nesline M, Conroy JM, DePietro P, Lippman SM, Kato S., Free PMC Article

    09/12/2024
    Role of TIM-3 in ovarian cancer: the forsaken cop or a new noble.

    Role of TIM-3 in ovarian cancer: the forsaken cop or a new noble.
    Chang X, Miao J., Free PMC Article

    09/12/2024
    Inhibitory Checkpoint Receptor TIM-3 as a Regulator of the Functional Activity of Dendritic Cells.

    Inhibitory Checkpoint Receptor TIM-3 as a Regulator of the Functional Activity of Dendritic Cells.
    Tyrinova TV, Chernykh ER.

    09/9/2024
    Impairment of Gal-9 and Tim-3 crosstalk between Tregs and Th17 cells drives tobacco smoke-induced airway inflammation.

    Impairment of Gal-9 and Tim-3 crosstalk between Tregs and Th17 cells drives tobacco smoke-induced airway inflammation.
    Qiu S, Zhou G, Ke J, Zhou J, Zhang H, Jin Z, Xie W, Huang S, He Z, Qin H, Huang H, Li Q, Huang H, Tang H, Liang Y, Duan M.

    08/21/2024
    The expression of TIM-3 and Gal-9 on macrophages and Hofbauer cells in the placenta of preeclampsia patients.

    The expression of TIM-3 and Gal-9 on macrophages and Hofbauer cells in the placenta of preeclampsia patients.
    Mittelberger J, Seefried M, Löb S, Kuhn C, Franitza M, Garrido F, Ditsch N, Jeschke U, Dannecker C.

    08/12/2024
    T-cell Immunoglobulin and Mucin Domain 3 in Circulating Monocytes as a Novel Biomarker for Coronary Artery Disease.

    T-cell Immunoglobulin and Mucin Domain 3 in Circulating Monocytes as a Novel Biomarker for Coronary Artery Disease.
    Xiao F, Jia Z, Wang L, Liu M, Chen X, Gu Z, Chen Y, Li Y, Chen M, Hong M.

    07/24/2024
    TIM-3 Expression in Endometriosis.

    TIM-3 Expression in Endometriosis.
    Lourenço Reis J, Martins C, Ângelo-Dias M, Rosa NN, Borrego LM, Lima J.

    07/4/2024
    Association of tuberculosis risk with genetic polymorphisms of the immune checkpoint genes PDCD1, CTLA-4, and TIM3.

    Association of tuberculosis risk with genetic polymorphisms of the immune checkpoint genes PDCD1, CTLA-4, and TIM3.
    Liu CW, Wu LS, Lin CJ, Wu HC, Liu KC, Lee SW., Free PMC Article

    06/13/2024
    A potential defensive role of TIM-3 on T lymphocytes in the inflammatory involvement of diabetic kidney disease.

    A potential defensive role of TIM-3 on T lymphocytes in the inflammatory involvement of diabetic kidney disease.
    Chen XJ, Tang R, Zha J, Zeng L, Zhou L, Liu Z, Yang D, Zeng M, Zhu X, Chen A, Liu H, Chen H, Chen G., Free PMC Article

    06/6/2024
    The role of TIM-3 in sepsis: a promising target for immunotherapy?

    The role of TIM-3 in sepsis: a promising target for immunotherapy?
    Wang C, Liu J, Wu Q, Wang Z, Hu B, Bo L., Free PMC Article

    04/12/2024
    TIM3 and CTLA4 immune checkpoint polymorphisms are associated with acute myeloid leukemia in Saudi Arabia.

    TIM3 and CTLA4 immune checkpoint polymorphisms are associated with acute myeloid leukemia in Saudi Arabia.
    Alqahtani M, Aljuaimlani A, Al-Tamimi J, Alomar S, Mansour L.

    03/29/2024
    Diffuse large B-cell lymphoma: the significance of CD8[+] tumor-infiltrating lymphocytes exhaustion mediated by TIM3/Galectin-9 pathway.

    Diffuse large B-cell lymphoma: the significance of CD8(+) tumor-infiltrating lymphocytes exhaustion mediated by TIM3/Galectin-9 pathway.
    Zhu Q, Yang Y, Chen K, Zhang Q, Huang Y, Jian S., Free PMC Article

    03/21/2024
    Beyond T cell exhaustion: TIM-3 regulation of myeloid cells.

    Beyond T cell exhaustion: TIM-3 regulation of myeloid cells.
    Dixon KO, Lahore GF, Kuchroo VK.

    03/13/2024
    The balance between CD4+ T helper 17 and T-cell immunoglobulin and mucin domain 3 is involved in the pathogenesis and development of atrial fibrillation.

    The balance between CD4+ T helper 17 and T-cell immunoglobulin and mucin domain 3 is involved in the pathogenesis and development of atrial fibrillation.
    Dai W, Zhang J, Wang Y, Zhou J, Dai Q, Lv J., Free PMC Article

    02/21/2024
    TIM-3/Galectin-9 interaction and glutamine metabolism in AML cell lines, HL-60 and THP-1.

    TIM-3/Galectin-9 interaction and glutamine metabolism in AML cell lines, HL-60 and THP-1.
    Shapourian H, Ghanadian M, Eskandari N, Shokouhi A, Demirel GY, Bazhin AV, Ganjalikhani-Hakemi M., Free PMC Article

    02/5/2024
    Expression of B7-H3 and TIM-3 in gastric-type endocervical adenocarcinoma: prevalence, association with PD-L1 expression, and prognostic significance.

    Expression of B7-H3 and TIM-3 in gastric-type endocervical adenocarcinoma: prevalence, association with PD-L1 expression, and prognostic significance.
    Sun Y, Zhou X, Lucas E, Chen L, Zhang H, Chen H, Zhou F., Free PMC Article

    01/5/2024
    Relationship between TIM3 Expression on Peripheral T Lymphocytes and Post-Stroke Depression.

    Relationship between TIM3 Expression on Peripheral T Lymphocytes and Post-Stroke Depression.
    Mao Q, Zhang P, Qi W, Xia Y, Chen T, Li X, Xu S, Zhong Z, Shangguan Z.

    01/5/2024
    [Significance of Tim-3 and Its Ligand Galectin-9 in Th1/Th2 Imbalance in Patients with Multiple Myeloma].

    [Significance of Tim-3 and Its Ligand Galectin-9 in Th1/Th2 Imbalance in Patients with Multiple Myeloma].
    Zhang R, Chen S, Luo TT, Qu JH.

    12/28/2023
    Activated Tim-3/Galectin-9 participated in the development of multiple myeloma by negatively regulating CD4 T cells.

    Activated Tim-3/Galectin-9 participated in the development of multiple myeloma by negatively regulating CD4 T cells.
    Zhang R, Chen S, Luo T, Guo S, Qu J.

    12/20/2023
    Case Report: HAVCR2 mutation-associated Hemophagocytic lymphohistiocytosis.

    Case Report: HAVCR2 mutation-associated Hemophagocytic lymphohistiocytosis.
    Song D, Wang J, Zhang J, Hu J, Wu C, Wang Z., Free PMC Article

    12/20/2023
    TIM-3/Gal-9 interaction affects glucose and lipid metabolism in acute myeloid leukemia cell lines.

    TIM-3/Gal-9 interaction affects glucose and lipid metabolism in acute myeloid leukemia cell lines.
    Rezaei M, Ghanadian M, Ghezelbash B, Shokouhi A, Bazhin AV, Zamyatnin AA Jr, Ganjalikhani-Hakemi M., Free PMC Article

    12/4/2023
    Tim-3 Is Differentially Expressed during Cell Activation and Interacts with the LSP-1 Protein in Human Macrophages.

    Tim-3 Is Differentially Expressed during Cell Activation and Interacts with the LSP-1 Protein in Human Macrophages.
    Ocaña-Guzman R, Ramon-Luing LA, Vazquez-Bolaños LA, Rodríguez-Alvarado M, Bulhusen-Rodriguez F, Torres-Hatem A, Gonzalez-Torres K, de Alba-Alvarado MC, Sada-Ovalle I., Free PMC Article

    11/21/2023
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