| P. Gingivalis induce macrophage polarization by regulating hepcidin expression in chronic apical periodontitis. | P. Gingivalis induce macrophage polarization by regulating hepcidin expression in chronic apical periodontitis.
Dou J, Chen X, Zhang J, Yang L, Lin J, Zhu W, Huang D, Tan X. | 10/17/2024 |
| Hepcidin deficiency impairs hippocampal neurogenesis and mediates brain atrophy and memory decline in mice. | Hepcidin deficiency impairs hippocampal neurogenesis and mediates brain atrophy and memory decline in mice.
Bai X, Wang B, Cui Y, Tian S, Zhang Y, You L, Chang YZ, Gao G., Free PMC Article | 01/16/2024 |
| A Decrease in Maternal Iron Levels Is the Predominant Factor Suppressing Hepcidin during Pregnancy in Mice. | A Decrease in Maternal Iron Levels Is the Predominant Factor Suppressing Hepcidin during Pregnancy in Mice.
Helman SL, Wilkins SJ, Chan JCJ, Hartel G, Wallace DF, Anderson GJ, Frazer DM., Free PMC Article | 10/25/2023 |
| Role of hepcidin upregulation and proteolytic cleavage of ferroportin 1 in hepatitis C virus-induced iron accumulation. | Role of hepcidin upregulation and proteolytic cleavage of ferroportin 1 in hepatitis C virus-induced iron accumulation.
Ohta K, Ito M, Chida T, Nakashima K, Sakai S, Kanegae Y, Kawasaki H, Aoshima T, Takabayashi S, Takahashi H, Kawata K, Shoji I, Sawasaki T, Suda T, Suzuki T., Free PMC Article | 08/31/2023 |
| Hepcidin deficiency in mice impairs white adipose tissue browning possibly due to a defect in de novo adipogenesis. | Hepcidin deficiency in mice impairs white adipose tissue browning possibly due to a defect in de novo adipogenesis.
Deschemin JC, Ransy C, Bouillaud F, Chung S, Galy B, Peyssonnaux C, Vaulont S., Free PMC Article | 08/9/2023 |
| Bone-derived C-terminal FGF23 cleaved peptides increase iron availability in acute inflammation. | Bone-derived C-terminal FGF23 cleaved peptides increase iron availability in acute inflammation.
Courbon G, Thomas JJ, Martinez-Calle M, Wang X, Spindler J, Von Drasek J, Hunt-Tobey B, Mehta R, Isakova T, Chang W, Creemers JWM, Ji P, Martin A, David V., Free PMC Article | 07/23/2023 |
| Intracellular labile iron is a key regulator of hepcidin expression and iron metabolism. | Intracellular labile iron is a key regulator of hepcidin expression and iron metabolism.
Li Y, Ouyang Q, Chen Z, Chen W, Zhang B, Zhang S, Cong M, Xu A. | 05/30/2023 |
| Genetic Iron Overload Hampers Development of Cutaneous Leishmaniasis in Mice. | Genetic Iron Overload Hampers Development of Cutaneous Leishmaniasis in Mice.
Charlebois E, Li Y, Wagner V, Pantopoulos K, Olivier M., Free PMC Article | 02/4/2023 |
| Hepcidin regulates neuronal ferroptosis: A mechanism for postoperative cognitive dysfunction. | Hepcidin regulates neuronal ferroptosis: A mechanism for postoperative cognitive dysfunction.
Shen H, Zhai L, Wang G. | 11/19/2022 |
| Astrocyte-derived hepcidin controls iron traffic at the blood-brain-barrier via regulating ferroportin 1 of microvascular endothelial cells. | Astrocyte-derived hepcidin controls iron traffic at the blood-brain-barrier via regulating ferroportin 1 of microvascular endothelial cells.
You L, Yu PP, Dong T, Guo W, Chang S, Zheng B, Ci Y, Wang F, Yu P, Gao G, Chang YZ., Free PMC Article | 08/6/2022 |
| Investigating the Molecular Mechanisms of Renal Hepcidin Induction and Protection upon Hemoglobin-Induced Acute Kidney Injury. | Investigating the Molecular Mechanisms of Renal Hepcidin Induction and Protection upon Hemoglobin-Induced Acute Kidney Injury.
Diepeveen LE, Stegemann G, Wiegerinck ET, Roelofs R, Naber M, Lóreal O, Smeets B, Thévenod F, Swinkels DW, van Swelm RPL., Free PMC Article | 03/5/2022 |
| Aging is associated with increased brain iron through cortex-derived hepcidin expression. | Aging is associated with increased brain iron through cortex-derived hepcidin expression.
Sato T, Shapiro JS, Chang HC, Miller RA, Ardehali H., Free PMC Article | 02/26/2022 |
| Salmonella effector SpvB aggravates dysregulation of systemic iron metabolism via modulating the hepcidin-ferroportin axis. | Salmonella effector SpvB aggravates dysregulation of systemic iron metabolism via modulating the hepcidin-ferroportin axis.
Deng Q, Yang S, Sun L, Dong K, Li Y, Wu S, Huang R., Free PMC Article | 01/22/2022 |
| Involvement of Hepcidin in Cognitive Damage Induced by Chronic Intermittent Hypoxia in Mice. | Involvement of Hepcidin in Cognitive Damage Induced by Chronic Intermittent Hypoxia in Mice.
Zhao YS, Tan M, Song JX, An JR, Yang XY, Li WY, Guo YJ, Ji ES., Free PMC Article | 01/8/2022 |
| Hepatocyte neogenin is required for hemojuvelin-mediated hepcidin expression and iron homeostasis in mice. | Hepatocyte neogenin is required for hemojuvelin-mediated hepcidin expression and iron homeostasis in mice.
Enns CA, Jue S, Zhang AS., Free PMC Article | 12/4/2021 |
| Oral Administration of Ginger-Derived Lipid Nanoparticles and Dmt1 siRNA Potentiates the Effect of Dietary Iron Restriction and Mitigates Pre-Existing Iron Overload in Hamp KO Mice. | Oral Administration of Ginger-Derived Lipid Nanoparticles and Dmt1 siRNA Potentiates the Effect of Dietary Iron Restriction and Mitigates Pre-Existing Iron Overload in Hamp KO Mice.
Wang X, Zhang M, Woloshun RR, Yu Y, Lee JK, Flores SRL, Merlin D, Collins JF., Free PMC Article | 08/7/2021 |
| Hepcidin-induced reduction in iron content and PGC-1beta expression negatively regulates osteoclast differentiation to play a protective role in postmenopausal osteoporosis. | Hepcidin-induced reduction in iron content and PGC-1β expression negatively regulates osteoclast differentiation to play a protective role in postmenopausal osteoporosis.
Zhang H, Wang A, Shen G, Wang X, Liu G, Yang F, Chen B, Wang M, Xu Y., Free PMC Article | 08/7/2021 |
| Leishmania infection triggers hepcidin-mediated proteasomal degradation of Nramp1 to increase phagolysosomal iron availability. | Leishmania infection triggers hepcidin-mediated proteasomal degradation of Nramp1 to increase phagolysosomal iron availability.
Banerjee S, Datta R. | 08/7/2021 |
| Hepcidin gene silencing ameliorated inflammation and insulin resistance in adipose tissue of db/db mice via inhibiting METs formation. | Hepcidin gene silencing ameliorated inflammation and insulin resistance in adipose tissue of db/db mice via inhibiting METs formation.
Zhang X, Zhang L, Tan YM, Liu YP, Li JJ, Deng QM, Yan SB, Zhang W, Han L, Zhong M. | 06/26/2021 |
| Gnpat does not play an essential role in systemic iron homeostasis in murine model. | Gnpat does not play an essential role in systemic iron homeostasis in murine model.
An P, Wang J, Wang H, Jiang L, Wang J, Min J, Wang F., Free PMC Article | 05/1/2021 |
| Fetal liver hepcidin secures iron stores in utero. | Fetal liver hepcidin secures iron stores in utero.
Kämmerer L, Mohammad G, Wolna M, Robbins PA, Lakhal-Littleton S., Free PMC Article | 03/27/2021 |
| Hepcidin is not essential for mediating testosterone's effects on erythropoiesis. | Hepcidin is not essential for mediating testosterone's effects on erythropoiesis.
Guo W, Schmidt PJ, Fleming MD, Bhasin S. | 01/23/2021 |
| Local hepcidin increased intracellular iron overload via the degradation of ferroportin in the kidney. | Local hepcidin increased intracellular iron overload via the degradation of ferroportin in the kidney.
Pan S, Qian ZM, Cui S, Zhao D, Lan W, Wang X, Chen X. | 08/15/2020 |
| ERFE also inhibited hepcidin induction by BMP6. In contrast, although hepcidin levels were lower in cells treated with BMP2 and ERFE compared with BMP2 treatment alone, the fold-induction was not reduced after adjusting for lower basal hepcidin levels in ERFE-treated control mice ERFE also inhibited hepcidin induction by BMP6. | Erythroferrone lowers hepcidin by sequestering BMP2/6 heterodimer from binding to the BMP type I receptor ALK3.
Wang CY, Xu Y, Traeger L, Dogan DY, Xiao X, Steinbicker AU, Babitt JL., Free PMC Article | 07/25/2020 |
| Hepcidin role in the iron homeostasis. | Genetic background influences hepcidin response to iron imbalance in a mouse model of hemolytic anemia (Congenital erythropoietic porphyria).
Lefebvre T, Millot S, Richard E, Blouin JM, Lalanne M, Lamrissi-Garcia I, Costet P, Lyoumi S, Gouya L, Puy H, Moreau-Gaudry F, de Verneuil H, Karim Z, Ged C. | 07/25/2020 |